By Dr. Omer Hassan Aftab Ahmed
Reviewed By Dr. Huma Ameer
By Dr. Omer Hassan Aftab Ahmed
Reviewed By Dr. Huma Ameer
Causing adverse reactions upon ingesting gluten, the constituent protein of wheat, barley and rye, Celiac Disease is one ring above Gluten Intolerance in that it is a chronic autoimmune disorder that slowly damages the small intestine due to continued gluten use. Affecting more than 1 in 100 people worldwide according to celiac.org, celiac disease can develop at any age and can reduce quality of life in adults while negatively affecting growth and development in children.
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Due to a genetic defect, the immune system mistakenly identifies and attacks gluten-containing food when it reaches the small intestine. The tiny hair-like projections called ‘villi’ that line the small intestine and are responsible for absorbing nutrients from food are caught in the crossfire and damaged. Over time, the continued destruction of villi every time a gluten-containing food is ingested reduces the amount of nutrients absorbed by the body, hence resulting in multiple nutritional deficiencies and exposing the body to numerous health conditions.
Like its effects, the symptoms of celiac disease vary in children and adults:
Under 2 Years:
Over 2 Years:
While the actual cause is as undetermined, scientists have concluded that the presence of the HLA-DQ2 and/or HLA-DQ8 genes inherited from one or both parents is the primary cause of the condition’s characteristic autoimmune reactions in most affected individuals. Moreover, the condition may also be triggered following childbirth, a viral infection, surgery, or severe emotional stress, or even during pregnancy, in some individuals.
While celiac disease can affect anyone regardless of age, gender, or ethnicity, presence of the following factors may increase the risk of disease development:
Untreated celiac disease can instigate the following health conditions:
Although celiac disease may not be easily detectable in most individuals, experiencing any relevant symptoms, like paleness, irritability, potbellies, foul-smelling, bulky stools, and stunted growth in children, and diarrhea or prolonged digestive discomfort in adults, requires urgent medical consultation. You can also book an appointment with a top Gastroenterologist in Lahore, Karachi and Rawalpindi through oladoc.com, or call our helpline at 042-3890-0939 for assistance to find the RIGHT Doctor for your gastric concerns.
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