4G-Foli Tablet 400mcg

About 4G-Foli Tablet 400mcg

4G-Foli Tablet 400mcg Uses

• Supporting healthy neural tube development in early pregnancy
• Correcting or preventing folate deficiency
• Supporting red blood cell formation and preventing megaloblastic anemia
• Helping women trying to conceive build folate stores before pregnancy
• Supporting maternal nutrition during breastfeeding

4G-Foli Tablet 400mcg Benefits

• Absorbed directly without needing liver conversion, unlike plain folic acid
• Lowers the risk of neural tube defects such as spina bifida
• Supports healthy fetal brain and spinal cord growth
• Helps reduce pregnancy related fatigue linked to low folate
• Suitable for women with common folate metabolism gene variants

What Experts Say

Doctors often prefer L-Methylfolate over plain folic acid because it is already in the active form the body uses directly. Roughly one in three people carry a gene variant that slows conversion of folic acid into its usable form, so the pre-converted molecule ensures adequate folate reaches the fetus exactly when the neural tube is forming.

Neural tube defects remain more common in Pakistan than in many neighbouring countries, and folate deficiency is widespread because diets often lack leafy greens, legumes and fortified grains. Many pregnancies are also unplanned, so women frequently start folate supplementation only after conception, well past the critical early window when the tube closes.

4G-Foli is generally well tolerated and rarely causes side effects beyond mild nausea if taken on an empty stomach. It should not mask an underlying vitamin B12 deficiency, so anyone with unexplained tiredness or tingling in the hands or feet should get B12 levels checked before long-term use.

Drug Class

• Vitamin B9 derivative (active folate)
• Prenatal nutritional supplement

4G-Foli Tablet 400mcg formula

• L-Methylfolate 400mcg

Available forms

• Tablet

How to use 4G-Foli Tablet 400mcg?

• Take one tablet daily, preferably with a meal
• Swallow the tablet whole with a glass of water
• Start supplementation ideally before conception and continue through the first trimester
• Do not exceed the dose recommended by your doctor

Drug Interactions

4G-Foli can interact with certain medicines that affect folate metabolism, so tell your doctor about everything you are taking.

• Anti-Epileptic Drugs: Phenytoin, carbamazepine and valproate levels can be affected by high dose folate, requiring monitoring.
• Methotrexate: Folate can reduce the effectiveness of methotrexate used for cancer or autoimmune conditions.
• Sulfasalazine: This drug can lower folate absorption, so timing may need adjustment.

Risks and warnings

• Vitamin B12 Masking: High folate intake can hide the blood signs of B12 deficiency, delaying diagnosis of nerve damage.
• Allergy: Stop use and consult a doctor if you notice rash, itching or swelling after taking this tablet.
• Underlying Conditions: Inform your doctor if you have kidney disease or a history of seizures before starting long term folate therapy.

4G-Foli Tablet 400mcg Side Effects

Most women tolerate 4G-Foli well, and side effects are usually mild and temporary.

• Mild nausea
• Bloating or gas
• Metallic or bitter taste in the mouth
• Loss of appetite

Contact your doctor or seek medical help if you notice any of the following serious effects.

• Skin rash, itching or hives
• Swelling of the face, lips or throat
• Difficulty breathing
• Unusual fatigue with numbness or tingling in hands or feet

Storage Conditions

• Store below 30°C in a cool, dry place
• Keep away from direct sunlight and moisture
• Keep the strip in its original packaging until use
• Keep out of reach of children