Alzilo Tablet 20mg / 120mg

About Alzilo Tablet 20mg / 120mg

Alzilo Tablet 20mg / 120mg Uses

• Treats the movement symptoms of Parkinson's disease, including tremor and stiffness.
• Used as monotherapy in early Parkinson's disease.
• Used as add on therapy with levodopa in more advanced Parkinson's disease.
• Helps reduce off periods when levodopa's effect wears off between doses.

Alzilo Tablet 20mg / 120mg Benefits

• Once daily dosing improves ease of use for older patients.
• Slows the breakdown of dopamine in the brain, supporting smoother movement control.
• Can reduce the total daily dose of levodopa needed in combination therapy.
• May help shorten daily off time in patients with motor fluctuations.

What Experts Say

Rasagiline works by selectively inhibiting monoamine oxidase type B, the enzyme responsible for breaking down dopamine in the brain. By blocking this pathway, more dopamine remains available at nerve synapses, which helps ease the tremor, rigidity and slowness that define Parkinson's disease.

Neurologists often prefer a selective MAO-B inhibitor early in the disease course because it carries a lower risk of the dietary tyramine reaction seen with older, non selective MAO inhibitors. Even so, physicians still advise caution with certain antidepressants and opioid pain medicines, since combining these drug classes can raise the risk of serotonin syndrome.

When added to levodopa in more advanced disease, rasagiline extends the on time patients experience each day by slowing dopamine breakdown between levodopa doses. Movement specialists typically monitor blood pressure, mood and liver function during treatment, since sudden drops in blood pressure and mood changes have been reported with this drug class.

Drug Class

• Selective Monoamine Oxidase Type B (MAO-B) Inhibitor
• Antiparkinsonian Agent

Alzilo Tablet 20mg / 120mg formula

• Rasagiline

Available forms

• Tablet

How to use Alzilo Tablet 20mg / 120mg?

• Take Alzilo Tablet exactly as prescribed by your neurologist.
• Swallow the tablet whole with a glass of water, with or without food.
• Take it at the same time every day to maintain a steady effect.
• Do not stop the medicine suddenly without your doctor's advice.
• Avoid tyramine rich foods like aged cheese, cured meats and soy sauce while on treatment.

Drug Interactions

• MAO inhibitors: Must not be combined, wait at least 14 days between switching drugs.
• SSRIs and SNRIs: Increase the risk of serotonin syndrome when combined.
• Meperidine and tramadol: Can cause a dangerous interaction, avoid combined use.
• Dextromethorphan: Found in many cough syrups, avoid while on this medicine.
• Ciprofloxacin: Can raise rasagiline levels in the blood, dose adjustment may be needed.

Risks and warnings

• Serotonin syndrome: Risk increases when combined with antidepressants, tramadol or St. John's Wort.
• Blood pressure changes: May cause a sudden rise or fall in blood pressure, especially with tyramine rich foods.
• Mood and behavior changes: Can cause hallucinations, impulse control problems or worsened depression.
• Liver impairment: Use with caution and lower doses in patients with liver disease.
• Skin cancer risk: Parkinson's patients on this drug class need regular skin checks.

Alzilo Tablet 20mg / 120mg Side Effects

• Nausea and dry mouth
• Joint pain and back pain
• Depressed mood or anxiety
• Difficulty sleeping or unusual dreams
• Swelling of the hands or feet
• Sudden drowsiness during daily activities
• Hallucinations or confusion
• Uncontrolled jerky movements (dyskinesia)

Storage Conditions

• Store below 30°C in a cool, dry place away from direct sunlight.
• Keep the tablets in their original blister strip until ready to use.
• Keep out of reach of children.
• Do not use after the expiry date printed on the pack.