About Amdaquin Tablet 150mg
Amdaquin Tablet 150mg contains Amodiaquine, used for treatment of malaria.
Amdaquin Tablet 150mg Uses
- Treats uncomplicated malaria caused by Plasmodium falciparum and Plasmodium vivax
- Used with artesunate as part of combination therapy for malaria in some treatment regimens
- Clears malaria parasites from the blood and relieves fever, chills and body aches caused by the infection
Drug Class
- Belongs to the 4-aminoquinoline group of antimalarial medicines, the same family as chloroquine
What Experts Say
Amodiaquine belongs to an older class of antimalarial medicines called 4-aminoquinolines. Physicians have relied on this drug family for decades, and amodiaquine still works well in areas where malaria parasites remain sensitive to it. Doctors usually confirm malaria with a blood test before starting any treatment course.
Combination therapy is common in current malaria care. Many prescribers pair amodiaquine with artesunate, since this combination clears parasites faster and lowers the chance of resistance building up. The World Health Organization lists artesunate plus amodiaquine as one recommended option for uncomplicated falciparum malaria.
Repeated or prolonged use raises genuine safety concerns. Amodiaquine carries a higher risk of liver injury and blood cell problems than chloroquine, so doctors reserve it for confirmed treatment courses rather than routine prevention. Blood counts and liver function tests are advised whenever a patient needs more than one course within a short period.
Amdaquin Tablet 150mg Uses in Urdu
- ملیریا کے مرض کا علاج جو پلازموڈیم فالسیپیرم اور پلازموڈیم ویویکس کی وجہ سے ہوتا ہے
- بخار، سردی لگنا اور جسم میں درد جیسی ملیریا کی علامات میں کمی
- بعض اوقات آرٹی سیونیٹ کے ساتھ ملا کر علاج کے لیے استعمال کی جاتی ہے
Amdaquin Tablet 150mg formula
How to use Amdaquin Tablet 150mg?
- Take Amdaquin exactly as prescribed by your doctor, based on your body weight and the severity of infection
- Swallow the tablet with water, preferably after a meal to reduce stomach upset
- Complete the full course even if fever and other symptoms improve after a day or two
- Do not use this medicine on your own to prevent malaria before travel, it is meant for treating an active infection
- Contact your doctor immediately if fever does not settle within 48 to 72 hours of starting treatment
Drug Interactions
- Mefloquine: Combining these two antimalarials raises the risk of seizures and heart rhythm problems
- Efavirenz: This HIV medicine taken with amodiaquine has been linked to serious liver injury and is generally avoided together
- Gemfibrozil: This cholesterol medicine can raise amodiaquine levels in the blood and increase side effects
- Other liver affecting medicines: Taking amodiaquine with other drugs that stress the liver can add to the risk of liver injury
- Bone marrow suppressing drugs: Using these together can raise the chance of low blood cell counts
Risks and warnings
- Liver problems: Amodiaquine can injure the liver, especially with repeated or prolonged courses, so doctors check liver function before repeat treatment
- Blood disorders: Rare but serious drops in white blood cells have been linked to this medicine, report unusual tiredness, fever or infections right away
- Heart rhythm changes: Avoid combining with other medicines that affect heart rhythm, since amodiaquine can affect the heart's electrical activity at higher doses
- G6PD deficiency: People with this inherited blood condition should use this medicine cautiously since it can trigger red blood cell breakdown
- Pregnancy: Use only if a doctor decides the benefit of treating malaria outweighs the risk, particularly in the first trimester
- Not for prevention: This tablet is meant for treating confirmed malaria, not for long-term prophylaxis before travel to malaria-prone areas
Amdaquin Tablet 150mg Side Effects
- Nausea and vomiting
- Stomach pain
- Headache and dizziness
- Itching of the skin
- Loss of appetite
- Blurred vision
- Yellowing of the skin or eyes, a sign of liver trouble
- Unusual bruising or bleeding, a sign of a blood problem
Storage Conditions
- Store below 30 degrees Celsius in a cool, dry place away from direct sunlight
- Keep the tablets in their original blister pack until you are ready to take a dose
- Keep this medicine out of reach and sight of children
- Do not use the tablet after the expiry date printed on the pack