Amole Plus Tablet 500mg/65mg

About Amole Plus Tablet 500mg/65mg

Uses

• Short term relief of moderate to severe pain
• Pain after surgery or dental procedures
• Pain from injuries, fractures, or sprains
• Chronic pain that has not responded well to Paracetamol alone
• Pain associated with osteoarthritis flare ups when advised by a doctor

Benefits

• Combines two pain relieving actions for a stronger effect than Paracetamol alone
• Works faster than single ingredient painkillers for moderate to severe pain
• Reduces the total opioid dose needed compared to Tramadol alone
• Available as an oral tablet, convenient for short courses at home

What Experts Say

Tramadol works on the brain and spinal cord to change how pain signals are processed, while Paracetamol adds a separate pain relieving and fever reducing effect, and combining both allows a lower dose of Tramadol to control pain. This dual action is why doctors reach for it when single agent painkillers fall short.

Pain specialists in Pakistan often prescribe this combination for short courses after surgery, dental work, or injury, since it controls pain that plain Paracetamol or NSAIDs cannot manage alone. It is generally reserved for situations where pain is expected to ease within a few days.

Because Tramadol is an opioid, doctors recommend using Amole Plus only for the shortest effective time, since longer use raises the risk of dependence, tolerance, and withdrawal symptoms on stopping. Patients with a history of substance misuse are usually monitored more closely or given alternatives.

Drug Class

• Opioid and non-opioid analgesic combination
• Centrally acting pain reliever

Amole Plus Tablet 500mg/65mg formula

• Paracetamol + Tramadol Hydrochloride

Available forms

• Tablet

How to use Amole Plus Tablet 500mg/65mg?

• Take Amole Plus tablet exactly as prescribed by the doctor, usually every 6 to 8 hours as needed for pain
• Swallow the tablet whole with a glass of water, with or without food
• Do not exceed the maximum daily dose set by the prescribing doctor
• Do not stop a long course suddenly without medical advice, since this can cause withdrawal symptoms
• Avoid alcohol while taking this medicine

Drug Interactions

• Other opioid pain medicines: Increases the risk of severe sedation and slowed breathing
• Antidepressants (SSRIs, SNRIs, MAOIs): Raises the risk of a serious condition called serotonin syndrome
• Sedatives and sleeping pills: Combined use deepens drowsiness and breathing suppression
• Warfarin and other blood thinners: May increase bleeding risk when combined with Tramadol
• Alcohol: Increases sedation, liver strain, and the risk of dangerous breathing problems

Risks and warnings

• Dependency and Misuse Risk: Contains Tramadol, an opioid, and carries a real risk of dependence, tolerance, and misuse with repeated use
• Breathing Suppression: Can slow breathing at higher doses, especially when combined with alcohol or sedatives
• Seizure Risk: May increase the risk of seizures, particularly in people with epilepsy or on certain antidepressants
• Liver Damage: High doses or long term use can harm the liver due to the Paracetamol component
• Not for Children: Not recommended for use in children under 12 years of age

Amole Plus Tablet Side Effects

• Nausea
• Dizziness
• Drowsiness
• Constipation
• Dry mouth
• Sweating
• Headache
• Vomiting
• Low blood pressure on standing up
• Confusion in older adults

Storage Conditions

• Store below 30°C in a dry place away from direct sunlight
• Keep the tablets in their original strip until the time of use
• Store securely out of reach of children and away from anyone with a history of substance misuse
• Discard any expired or unused tablets safely rather than keeping them at home