Antimal Plus Tablet 20mg / 120mg

About Antimal Plus Tablet 20mg / 120mg

Antimal Plus Tablet 20mg / 120mg Uses

• Uncomplicated Plasmodium falciparum malaria
• Malaria in adults and children over 5kg body weight
• Chloroquine-resistant falciparum malaria

Antimal Plus Tablet 20mg / 120mg Benefits

• Standard strength combination suited for weight based dosing
• Effective against chloroquine-resistant malaria strains
• Fast acting artemether component clears parasites quickly
• Widely used first line malaria treatment in Pakistan

What Experts Say

This standard strength combination pairs 20mg of artemether with 120mg of lumefantrine, the ratio most commonly used in weight based malaria dosing charts. Artemether clears the bulk of the parasites within the first day or two of treatment, bringing fever down quickly.

Lumefantrine then stays in the body longer and mops up any remaining parasites, preventing an early relapse. Because the tablet strength is lower than the double strength version, patients often need more tablets per dose, especially adults and larger children, spread across a six-dose course.

As with other artemisinin combination therapies, this medicine should be taken with fatty food to help the body absorb lumefantrine properly. A full course must be completed even if the fever and other symptoms improve within a day or two of starting treatment, since an incomplete course risks resistant malaria developing.

Drug Class

• Antimalarial combination
• Artemisinin-based combination therapy (ACT)

Antimal Plus Tablet 20mg / 120mg formula

• Artemether + Lumefantrine

Available forms

• Tablet

How to use Antimal Plus Tablet 20mg / 120mg?

• Take with fatty food or milk for better absorption
• Follow the weight based dosing schedule given by your doctor
• Complete the full course even if symptoms improve
• Do not double the dose if a dose is missed

Drug Interactions

• CYP3A4 Inhibitors: Certain antifungals and antibiotics can raise drug levels.
• Other QT-Prolonging Drugs: Increases the risk of heart rhythm disturbance when combined.
• Mefloquine or Quinine: Avoid combining with other antimalarials unless directed by a doctor.

Risks and warnings

• Heart Rhythm Disorders: Avoid in patients with known QT prolongation or irregular heartbeat.
• Pregnancy: Use only if clearly necessary and under medical supervision.
• Liver Disease: Use with caution and monitor liver function.
• Incomplete Course: Stopping early raises the risk of malaria relapse and drug resistance.

Antimal Plus Tablet 20mg / 120mg Side Effects

• Abdominal discomfort
• Loss of appetite
• Diarrhea
• Vomiting
• Nausea
• Dizziness
• Headache

Storage Conditions

• Store below 30°C in a dry place
• Protect from moisture and direct sunlight
• Keep in the original blister strip until each dose is due
• Keep out of reach of children