Avsar Plus Tablet 160mg/5mg/12.5mg

About Avsar Plus Tablet 160mg/5mg/12.5mg

Uses

• Treats high blood pressure (essential hypertension) in adults
• Used when blood pressure is not controlled well enough on a single blood pressure medicine
• Given as add-on therapy for patients already on two of the three components separately
• Helps reduce the long-term risk of heart attack, stroke and kidney damage linked to uncontrolled high blood pressure

Benefits

• Combines three complementary blood pressure lowering mechanisms in one tablet
• The 5mg amlodipine dose lowers the chance of ankle swelling compared to the 10mg strength
• Once daily dosing improves adherence to long-term hypertension treatment
• Valsartan and hydrochlorothiazide help counter the fluid retention that amlodipine alone can cause

What Experts Say

Physicians choose the amlodipine 5mg strength of Avsar Plus for patients who need blood pressure control from all three drug classes but cannot tolerate the peripheral edema or flushing that the 10mg amlodipine dose can cause. Amlodipine's ankle swelling risk is dose dependent, so stepping down the calcium channel blocker component while keeping valsartan and hydrochlorothiazide at their standard doses often preserves control with fewer complaints.

This strength also suits older patients and those with lower body weight, who generally need less calcium channel blockade to reach target blood pressure. Valsartan blocks angiotensin II receptors and hydrochlorothiazide promotes sodium and water loss, so the combination still delivers a strong antihypertensive effect even with the reduced amlodipine dose.

Doctors also use this 160mg, 5mg, 12.5mg formulation as a step between dual therapy and the higher amlodipine based combinations, allowing gradual dose titration instead of moving straight to the maximum strength. Regular monitoring of potassium, kidney function and blood pressure response guides whether a patient stays on this dose or moves up to 10mg amlodipine.

Drug Class

• Angiotensin Receptor Blocker (ARB)
• Calcium Channel Blocker (CCB)
• Thiazide Diuretic

Avsar Plus Tablet 160mg/5mg/12.5mg formula

• Valsartan + Amlodipine + Hydrochlorothiazide

Available forms

• Tablet

How to use Avsar Plus Tablet 160mg/5mg/12.5mg?

• Take one tablet daily, preferably in the morning, with or without food
• Swallow the tablet whole with a glass of water
• Take at the same time each day for consistent blood pressure control
• Do not stop the medicine suddenly without consulting your doctor

Drug Interactions

• Potassium supplements or potassium sparing diuretics can raise potassium to unsafe levels
• NSAIDs like ibuprofen may reduce the blood pressure lowering effect and affect kidney function
• Lithium levels can rise when taken along with this combination
• Other blood pressure lowering drugs can add to the blood pressure lowering effect
• Alcohol can increase dizziness and the risk of low blood pressure

Risks and warnings

• Not recommended during pregnancy, can cause fetal harm, especially in the second and third trimester
• Use with caution in patients with kidney or liver impairment
• May cause low blood pressure in patients who are dehydrated or already on other blood pressure medicines
• Can lower potassium and sodium levels, periodic blood tests are advised
• Stop immediately and seek medical help if swelling of the face, lips or throat occurs
• Not advised for patients with a known allergy to sulfonamide derived medicines

Avsar Plus Tablet 160mg/5mg/12.5mg Side Effects

• Dizziness
• Headache
• Fatigue
• Swelling in the ankles or feet
• Low potassium levels
• Upset stomach
• Increased cholesterol or blood sugar levels
• Muscle cramps
• Rare allergic reactions including facial swelling

Storage Conditions

• Store below 30°C in a cool, dry place
• Keep tablets in their original blister pack away from moisture and light
• Keep out of reach of children
• Do not use after the expiry date printed on the pack