Azafrine tablet 50mg

About Azafrine tablet 50mg

Azafrine Tablet Uses

• Preventing rejection after a kidney or other organ transplant
• Controlling rheumatoid arthritis that has not responded to other treatments
• Managing autoimmune conditions such as lupus and inflammatory bowel disease

Azafrine Tablet Benefits

• Lowers the immune system's attack on a transplanted organ
• Reduces joint pain, swelling, and stiffness in autoimmune arthritis
• Helps bring inflammatory bowel disease symptoms under control

Transplant centers in Lahore, Karachi, Islamabad, and Rawalpindi rely on Azafrine tablet 50mg to keep the body from rejecting a newly transplanted organ.

Rheumatologists also prescribe it for autoimmune conditions when first line treatments have not controlled symptoms well enough on their own.

This medicine needs regular blood monitoring since it affects the bone marrow and immune system.

Drug Class

• Immunosuppressant
• Purine analog

Azafrine tablet 50mg formula

• Azathioprine

Available forms

• Tablet

How to use Azafrine tablet 50mg?

• Take with food to reduce stomach upset
• Swallow the tablet whole, do not crush or split it
• Take it at the same time every day as prescribed
• Attend all scheduled blood tests during treatment
• Do not stop the medicine suddenly without your doctor's advice

Drug Interactions

• Allopurinol: This gout medicine blocks the breakdown of azathioprine and can cause severe toxicity, so the azathioprine dose must be reduced.
• ACE Inhibitors: Combined use may increase the risk of low blood counts and anemia.
• Live Vaccines: Live vaccines should be avoided while on azathioprine because immunity is suppressed.
• Warfarin: Azathioprine may reduce the blood thinning effect of warfarin, so closer monitoring is needed.

Risks and warnings

• Bone Marrow Suppression: Azathioprine can lower red blood cells, white blood cells, and platelets, so regular blood counts are essential.
• Infection Risk: A weakened immune system makes infections more likely and harder for the body to fight off.
• Liver Toxicity: This medicine can affect liver function, so periodic liver tests are needed during treatment.
• TPMT Deficiency: People with low levels of the TPMT enzyme face a higher risk of severe toxicity and may need testing before starting.
• Pregnancy Caution: Azathioprine should only be used in pregnancy under close specialist supervision.

Side Effects

• Nausea and vomiting
• Loss of appetite
• Increased risk of infections
• Mouth sores
• Hair thinning
• Skin rash
• Unusual tiredness

Storage Conditions

Store Azafrine tablets at room temperature, below 30 degrees Celsius, away from moisture and direct sunlight. Keep the tablets in their original strip until use. Keep out of reach of children.