Bexus injection 500mg

About Bexus injection 500mg

Bexus injection 500mg Uses

• Hospital acquired and community acquired pneumonia
• Complicated urinary tract infections and pyelonephritis
• Complicated skin and soft tissue infections
• Intra abdominal infections
• Chronic bacterial prostatitis

Drug Class

• Fluoroquinolone antibiotic
• Broad spectrum antibacterial agent

What Experts Say

Levofloxacin works by blocking bacterial DNA gyrase and topoisomerase IV, enzymes bacteria need to copy their DNA and multiply. Given directly into the bloodstream, it reaches therapeutic levels quickly, which matters in severe infections.

Bexus injection is given slowly over about 60 to 90 minutes through an IV line, usually once daily, by trained hospital staff. Patients are often switched to oral levofloxacin once their condition improves.

It carries the same boxed warning for tendon rupture as oral levofloxacin, along with risks of nerve damage and heart rhythm changes. Infusion site irritation and a drop in blood pressure can occur if given too quickly.

Bexus injection 500mg formula

• Levofloxacin (as hemihydrate) 500mg

Available forms

• Injection (IV Infusion)

How to use Bexus injection 500mg?

• Given only as a slow intravenous infusion by trained medical staff.
• Usually infused once daily over 60 to 90 minutes.
• Not for intramuscular, subcutaneous, or intrathecal injection.
• Often followed by a switch to oral levofloxacin as the patient improves.

Drug Interactions

Bexus injection interacts with several medicines used in hospital settings.

• Warfarin: Can increase bleeding risk, so clotting levels should be monitored closely.
• NSAIDs: Combined use raises the risk of seizures and central nervous system effects.
• Corticosteroids: Increase the risk of tendon rupture, especially in older adults.
• Drugs that prolong QT interval: Combined use raises the risk of dangerous heart rhythm changes.

Risks and warnings

• Tendon damage: Can cause tendon rupture or tendinitis, more common after age 60 or with steroid use.
• Infusion reactions: Rapid infusion can cause low blood pressure, so it must be given slowly.
• Nerve effects: May cause peripheral neuropathy, sometimes irreversible.
• Heart rhythm: Can prolong the QT interval, requiring caution with existing heart conditions.
• Pregnancy: Avoid in pregnancy and while breastfeeding unless essential.

Bexus injection 500mg Side Effects

• Injection site irritation
• Nausea
• Headache
• Dizziness
• Low blood pressure with rapid infusion
• Tendon pain or swelling

Storage Conditions

Store below 25°C, protect from light and freezing, and keep out of reach of children.