About Biforge Tablet 10/160mg
Biforge 10mg/160mg Tablet combines amlodipine and valsartan to effectively lower and control high blood pressure.
Biforge Tablet Uses
- Used for high blood pressure (hypertension) in adults
- Given to patients with hypertension who need two medicines to control blood pressure
- Helpful in managing blood pressure that has not responded to a single medicine
- Effective against high blood pressure that raises the risk of heart attack or stroke
- Indicated for patients switching from separate amlodipine and valsartan tablets
- Supports treatment of hypertension in patients with cardiovascular risk factors
- Approved for adults requiring combination antihypertensive therapy as first-line treatment
Biforge Tablet Uses in Urdu
- یہ دوائی بالغوں میں ہائی بلڈ پریشر کے علاج کے لیے استعمال کی جاتی ہے۔
- یہ ان مریضوں کو دی جاتی ہے جن کا بلڈ پریشر ایک دوائی سے قابو میں نہیں آتا۔
- یہ خون کی نالیوں کو کشادہ کرکے دل پر پڑنے والا دباؤ کم کرتی ہے۔
- یہ فالج اور دل کے دورے کے خطرے کو کم کرنے میں مددگار ہے۔
- یہ ان مریضوں کے لیے تجویز کی جاتی ہے جن کو ہائی بلڈ پریشر کی وجہ سے دل کی بیماری کا خطرہ ہو۔
Biforge Tablet 10/160mg formula
Amlodipine 10 mg + Valsartan 160 mg
Available forms
- Biforge tablet - Amlodipine 5 mg + Valsartan 80 mg
- Biforge tablet - Amlodipine 5 mg + Valsartan 160 mg
How to use Biforge Tablet 10/160mg?
- Biforge tablets can be taken with or without food, at the same time each day.
- The tablet should be swallowed whole with a glass of water.
- Blood pressure checks are important during treatment to monitor the response to Biforge tablets.
- A dose should not be doubled if one is skipped; simply continue with the next scheduled dose.
Contraindications
- Known allergy to amlodipine, valsartan, or any ingredient in Biforge tablet
- Pregnancy, especially the second and third trimester, due to serious fetal harm
- Severe liver failure or severe obstruction of bile flow (cholestasis)
- Use with aliskiren in patients who also have diabetes
- Patients with a history of angioedema related to an ARB or ACE inhibitor
Drug Interactions
- Simvastatin: Amlodipine in Biforge tablet significantly increases simvastatin levels in the blood, raising the risk of muscle damage.
- Potassium-sparing diuretics (e.g., spironolactone): These can raise blood potassium levels further when combined with Biforge tablet.
- ACE inhibitors (e.g., enalapril): Combining with Biforge tablet increases the risk of low blood pressure, high potassium, and kidney problems.
- NSAIDs (e.g., ibuprofen, diclofenac): These can reduce the blood pressure-lowering effect of Biforge tablet and may worsen kidney function.
- Lithium: Valsartan in Biforge tablet may raise lithium levels in the blood, increasing the risk of lithium toxicity.
- Cyclosporine: This immunosuppressant may increase the blood levels of valsartan in Biforge tablet.
Risks and warnings
- Severe aortic stenosis: Biforge tablet must be used with extreme caution as low blood pressure can worsen this condition.
- Low blood volume or salt depletion: Biforge tablet may cause a sudden drop in blood pressure in patients on diuretics or with low fluid levels.
- Kidney artery narrowing (renal artery stenosis): Valsartan in Biforge tablet can reduce kidney function in these patients.
- Heart failure or recent heart attack: Biforge tablet should be started cautiously, as blood pressure may drop too low.
- High potassium levels (hyperkalemia): Valsartan in Biforge tablet may raise potassium, especially in patients with kidney disease.
- Pregnancy: Biforge tablet is strictly contraindicated in pregnancy due to risk of serious harm to the unborn baby.
- Breastfeeding: It is not known whether Biforge tablet passes into breast milk; a doctor's guidance is essential.
- Elderly patients: Older adults may be more sensitive to blood pressure changes with Biforge tablets and require dose adjustment.
- Liver problems: Patients with hepatic impairment should use Biforge tablets at a lower strength under supervision.
- Driving and machinery: Biforge tablet may cause dizziness, especially at the start of treatment, affecting the ability to drive.
Biforge Tablet Side Effects
- Swelling in the hands, ankles, or feet (peripheral edema)
- Dizziness or lightheadedness
- Headache
- Flushing (feeling of warmth in the face)
- Fatigue or tiredness
- Nausea
- Stuffy or runny nose
- Low blood pressure (hypotension)
- High potassium levels in the blood (hyperkalemia)
- Worsening of chest pain (angina), especially when first starting treatment
- Kidney function changes
- Allergic reactions including skin rash, swelling of the face or throat
Storage Conditions
- Store at room temperature, below 25°C
- Keep away from direct sunlight, heat, and moisture
- Keep out of reach of children and pets
