Brino Capsule 500 mg

About Brino Capsule 500 mg

Brino Capsule Uses

• Used for heavy menstrual bleeding (menorrhagia) in women of reproductive age
• Indicated for reducing blood loss during or after surgical procedures
• Helpful in managing nosebleeds (epistaxis) that are difficult to control
• Effective against bleeding during dental procedures and tooth extractions
• Approved for short-term management of bleeding in patients with hemophilia
• Treats abnormal bleeding caused by trauma or injury
• Supports control of bleeding in patients with certain clotting disorders

Brino Capsule 500 mg formula

• Tranexamic Acid 500mg

Available forms

• Brino capsule - 250mg
• Brino capsule - 500mg

How to use Brino Capsule 500 mg ?

• Brino capsule can be taken with or without food
• Swallow the capsule whole with a full glass of water
• A missed dose should be skipped if it is close to the next scheduled dose
• The capsule should not be crushed or chewed

Contraindications

• Patients with a history of blood clots (deep vein thrombosis, pulmonary embolism)
• Patients with retinal vein or artery occlusion
• Women currently using combined hormonal contraceptives (oral contraceptive pills)
• Patients with subarachnoid hemorrhage (bleeding between the brain and surrounding tissue)
• Patients with a known allergy to tranexamic acid or any component of this capsule
• Patients with color vision defects, as detecting toxicity becomes difficult

Drug Interactions

• Hormonal contraceptives (combined oral contraceptive pills): Combining these with Brino capsule significantly raises the risk of blood clots. This combination is contraindicated.
• Factor IX complex concentrates: Concurrent use increases the risk of dangerous clotting. These two medicines must not be used together.
• Anti-inhibitor coagulant concentrates: Using these alongside Brino capsule increases the risk of thrombosis. Avoid unless advised otherwise by a specialist.
• Tissue plasminogen activators (clot-dissolving medicines): Brino capsule reduces the effectiveness of these medicines and must be stopped if they are needed.
• All-trans retinoic acid (used in certain blood cancers): This combination carries a serious risk of thrombotic complications. It is not recommended.

Risks and warnings

• History of blood clots: Brino capsule increases clotting activity and is dangerous for patients with prior DVT, stroke, or embolism.
• Kidney impairment: Tranexamic acid is cleared through the kidneys. Dose reduction is necessary in patients with reduced kidney function.
• Visual disturbances: Any sudden change in vision while taking Brino capsule requires immediate discontinuation and urgent medical review.
• Seizure history: Tranexamic acid has been associated with seizures in some patients, particularly at higher doses.
• Color vision defects: Patients with this condition should not use Brino capsule, as signs of toxicity may go undetected.
• Pregnancy: This medicine should only be used during pregnancy if the benefit clearly outweighs the risk, under strict medical supervision.
• Breastfeeding: Tranexamic acid passes into breast milk in small amounts. A doctor's guidance is required before use.
• Elderly patients: Kidney function naturally declines with age. Dose adjustment may be needed in older adults.

Brino Capsule Side Effects

• Nausea or vomiting
• Stomach upset or abdominal pain
• Diarrhea or constipation
• Headache
• Dizziness
• Fatigue or general weakness
• Skin rash or itching
• Muscle cramps or joint pain
• Visual disturbances or blurred vision
• Swelling of the face, lips, or tongue (allergic reaction)
• Signs of blood clots such as chest pain, leg swelling, or sudden shortness of breath

Storage Conditions

• Store at room temperature, below 25°C
• Keep away from direct sunlight, heat, and moisture
• Keep out of reach of children and pets