Cebac Injection IV / IM 500mg / 500mg

About Cebac Injection IV / IM 500mg / 500mg

Cebac Injection IV / IM 500mg / 500mg Uses

• Treats moderate to severe respiratory tract infections including pneumonia and bronchitis
• Used for complicated urinary tract infections caused by susceptible bacteria
• Treats intra-abdominal infections such as peritonitis and cholecystitis
• Used in skin and soft tissue infections including cellulitis and wound infections
• Treats bone and joint infections in hospitalized patients
• Used for septicemia and other serious bloodstream infections
• Treats pelvic inflammatory disease and other gynecological infections

What Experts Say

Cefoperazone is a third generation cephalosporin that stops bacteria from building their cell walls, causing bacterial death. Sulbactam has weak antibacterial action on its own, but it blocks beta lactamase, an enzyme resistant bacteria use to destroy cefoperazone. Combining the two restores cefoperazone's activity against organisms that would otherwise resist it.

Doctors in Pakistan often choose this combination for moderate to severe infections when the exact organism and its resistance pattern are not yet known, since it covers a wide range of gram positive and gram negative bacteria. It is commonly used in hospital settings for infections that failed first line antibiotics. Culture and sensitivity testing before treatment helps confirm the organism is actually susceptible to this combination.

This medicine is given only as an injection, into a vein or a muscle, and is not available as a tablet or syrup. It should be administered by a trained healthcare professional who can monitor for allergic reactions, since cross reactivity with penicillin allergy is possible. Dose and duration depend on infection severity, kidney function, and the organism identified.

Cebac Injection IV / IM 500mg / 500mg formula

• Cefoperazone Sodium 500mg + Sulbactam Sodium 500mg

Available forms

• Injection

How to use Cebac Injection IV / IM 500mg / 500mg?

• Administered only by a doctor or nurse in a hospital or clinic setting
• Given as a slow intravenous infusion or as a deep intramuscular injection
• Reconstituted with the diluent provided or as directed before administration
• Dose and frequency are set by the treating physician based on infection severity and kidney function
• Complete the full prescribed course even if symptoms improve within a few days

Drug Interactions

• Anticoagulants: May increase the blood thinning effect of warfarin and similar drugs, raising bleeding risk
• Alcohol: Can cause a disulfiram like reaction with flushing, nausea and rapid heartbeat if consumed during treatment
• Aminoglycosides: Combined use may increase the risk of kidney related side effects
• Live Vaccines: Antibiotic therapy may reduce the effectiveness of live bacterial vaccines given around the same time

Risks and warnings

• Penicillin Allergy: Not suitable for patients with a known history of severe penicillin or cephalosporin allergy
• Kidney Or Liver Disease: Dose adjustment may be needed in patients with reduced kidney or liver function
• Pregnancy And Breastfeeding: Use only if clearly needed and under strict medical supervision
• Bleeding Risk: May affect vitamin K dependent clotting factors in some patients on prolonged therapy
• Superinfection: Prolonged use may lead to overgrowth of resistant bacteria or fungi

Cebac Injection IV / IM 500mg / 500mg Side Effects

• Pain, redness or swelling at the injection site
• Nausea, vomiting or diarrhea
• Skin rash or itching
• Headache
• Mild fever or chills
• Abnormal taste in the mouth
• Severe allergic reaction with swelling of the face, lips or throat
• Severe watery or bloody diarrhea suggesting a serious intestinal infection
• Unusual bleeding or bruising

Storage Conditions

• Store the unopened vial between 15 and 30 degrees Celsius, protected from light and moisture
• Use the reconstituted solution promptly as advised by the pharmacist or healthcare provider
• Do not use if the reconstituted solution is discolored or contains particles
• Keep out of reach of children