Cidine Tablet 1mg

About Cidine Tablet 1mg

Cidine Tablet 1mg Uses

• Gastroesophageal reflux disease (GERD)
• Functional dyspepsia
• Delayed gastric emptying
• Bloating and early fullness after meals
• Nausea linked to slow stomach emptying

Cidine Tablet 1mg Benefits

• Speeds up stomach emptying
• Reduces acid reflux symptoms
• Eases bloating and discomfort after eating
• Improves coordination of gut muscle contractions

What Experts Say

Cinitapride works by combining serotonergic and antidopaminergic actions in the gut. It stimulates 5-HT4 receptors and blocks 5-HT2 receptors, which increases the strength and coordination of stomach and esophageal muscle contractions. This dual action speeds gastric emptying and reduces the backward flow of stomach acid into the esophagus.

Clinical studies on cinitapride show measurable improvement in symptoms of functional dyspepsia, including early fullness, bloating and upper abdominal discomfort. Unlike older prokinetics, cinitapride has a lower affinity for cardiac potassium channels, which translates into a more favorable safety profile regarding heart rhythm disturbances.

Pharmacologically, cinitapride is metabolized in the liver and has a relatively short half life, supporting once to twice daily dosing before meals. Because it enhances gut motility without significantly affecting basal gastric acid secretion, it is often used alongside acid suppressing therapy rather than as a replacement for it.

Drug Class

• Gastroprokinetic agent
• Serotonergic agent (5-HT4 agonist, 5-HT2 antagonist)
• Gastrointestinal motility regulator

Cidine Tablet 1mg formula

• Cinitapride

Available forms

• Tablet

How to use Cidine Tablet 1mg?

• Take one tablet 2 to 3 times daily before meals, or as directed by your doctor
• Swallow the tablet whole with a glass of water
• Do not crush or chew the tablet
• Take at the same times each day for best results
• Do not exceed the dose recommended by your doctor

Drug Interactions

• Anticholinergic Drugs: May reduce the prokinetic effect of Cidine
• CNS Depressants: May increase drowsiness when combined with Cidine
• QT Prolonging Drugs: Use with caution when combined with other drugs that affect heart rhythm
• Alcohol: May increase drowsiness and dizziness

Risks and warnings

• Pregnancy: Use only if clearly needed and advised by a doctor, as safety in pregnancy is not fully established
• Breastfeeding: Consult your doctor before use while breastfeeding
• Liver Impairment: Use with caution in patients with liver disease
• Kidney Impairment: Dose adjustment may be needed in kidney disease
• Cardiac Conditions: Use with caution in patients with a history of heart rhythm problems

Cidine Tablet 1mg Side Effects

• Headache
• Dizziness
• Diarrhea
• Abdominal cramps
• Dry mouth
• Drowsiness
• Skin rash (rare)

Storage Conditions

• Store below 30°C in a cool, dry place
• Keep away from direct sunlight and moisture
• Keep out of reach of children
• Store in the original blister pack until use