Cimet Tablet 400mg

About Cimet Tablet 400mg

Cimet Tablet 400mg Uses

• Peptic ulcer disease
• Gastroesophageal reflux disease (GERD)
• Heartburn and acid indigestion
• Zollinger-Ellison syndrome
• Prevention of stress ulcers in hospitalized patients

Cimet Tablet 400mg Benefits

• Reduction in stomach acid production
• Relief from ulcer pain with support for healing
• Easing of heartburn and acid reflux symptoms
• An affordable generic option

What Experts Say

Cimetidine belongs to the H2-receptor antagonist class, which works by blocking histamine from binding to receptors on the acid-producing cells lining the stomach wall. This lowers the overall amount of acid the stomach produces throughout the day, both after meals and during fasting periods.

By reducing acid output, cimetidine allows an existing ulcer in the stomach or upper intestine to heal and reduces the burning sensation associated with acid reflux. It acts more slowly than proton pump inhibitors but remains useful for milder or intermittent symptoms.

Cimetidine is also recognized for inhibiting certain liver enzymes, which means it can raise blood levels of other drugs metabolized through the same pathway. Because of this interaction profile, doctors often prefer newer H2 blockers or proton pump inhibitors for long-term use, reserving cimetidine for shorter courses or cost-sensitive cases.

Drug Class

• H2-receptor antagonist
• Antisecretory / antiulcer agent

Cimet Tablet 400mg formula

• Cimetidine

Available forms

• Tablet

How to use Cimet Tablet 400mg?

• The tablet can be taken with or without food as advised by your doctor.
• The tablet should be swallowed whole with a glass of water.
• The last dose of the day is often taken at bedtime for ulcer healing.
• The full course should be completed even if symptoms improve early.
• A missed dose should not be doubled up at the next dose.

Drug Interactions

• Warfarin: Cimetidine can raise warfarin levels, increasing bleeding risk.
• Phenytoin: Blood levels of phenytoin may rise, requiring dose monitoring.
• Theophylline: Cimetidine can slow its clearance, raising the risk of toxicity.
• Ketoconazole: Reduced stomach acid from cimetidine can lower its absorption.
• Antacids: Antacids taken at the same time may reduce cimetidine absorption.

Risks and warnings

• Kidney Impairment: Dose adjustment is needed, as cimetidine is cleared through the kidneys.
• Elderly Patients: Higher risk of confusion or dizziness makes the lowest effective dose preferable.
• Liver Conditions: Caution is advised, as cimetidine can affect liver enzyme activity.
• Pregnancy and Breastfeeding: Use is recommended only if clearly advised by a doctor.
• Long-Term Use: Extended use without medical review may mask symptoms of a more serious stomach condition.

Cimet Tablet 400mg Side Effects

• Headache
• Dizziness
• Diarrhea
• Muscle pain
• Breast enlargement or tenderness in men with prolonged use
• Confusion, particularly in elderly or severely ill patients

Storage Conditions

• Store below 25°C in a dry place.
• Keep the strip in its original packaging until use.
• Protect from moisture and direct sunlight.
• Keep out of reach of children.
• Discard tablets after the printed expiry date.