Clomfranil Tablet 25mg

About Clomfranil Tablet 25mg

Clomfranil Tablet 25mg Uses

• Obsessive compulsive disorder (OCD)
• Major depressive disorder
• Panic disorder with or without agoraphobia
• Chronic neuropathic pain management
• Cataplexy linked with narcolepsy

Clomfranil Tablet 25mg Benefits

• Reduces intrusive thoughts and compulsive behaviors in OCD
• Improves low mood, sleep and appetite in depression
• Lowers frequency of panic attacks over continued use
• Helps control persistent nerve related pain
• Available as an affordable local generic of Clomipramine

What Experts Say

Clomipramine is the most serotonin selective tricyclic antidepressant available, which is why psychiatrists reach for it specifically in obsessive compulsive disorder when other options have not worked well enough. It blocks the reuptake of both serotonin and noradrenaline, but its stronger action on serotonin explains its particular usefulness in OCD compared to older tricyclics.

A 25mg strength usually sits within the maintenance range reached after gradual dose titration from a lower starting dose. Physicians build up slowly to this level to let the body adjust to anticholinergic effects such as dry mouth and constipation, while checking that the antidepressant or anti obsessional response is adequate before considering any further increase.

Because tricyclic antidepressants can affect heart rhythm, doctors often request a baseline ECG in patients with existing cardiac risk before prescribing this strength, and periodic review afterward. Sudden discontinuation is discouraged since it can trigger withdrawal like symptoms, so any dose change should always be guided by the prescribing physician.

Drug Class

• Tricyclic Antidepressant (TCA)

Clomfranil Tablet 25mg formula

• Clomipramine Hydrochloride

Available forms

• Tablet

How to use Clomfranil Tablet 25mg?

• Take exactly as prescribed by your psychiatrist or physician
• Swallow the tablet whole with a glass of water
• Take with or after food to reduce stomach upset
• Doses are usually increased gradually over several weeks
• Do not stop the tablet suddenly without medical advice

Drug Interactions

• MAOIs: Combining with monoamine oxidase inhibitors can cause a dangerous serotonin reaction
• SSRIs and SNRIs: Increases risk of serotonin syndrome when combined
• Other TCAs: Additive sedative and cardiac effects
• Alcohol: Increases drowsiness and impairs coordination
• Anticholinergic drugs: May worsen dry mouth, constipation and blurred vision
• Antihypertensive drugs: May alter blood pressure control

Risks and warnings

• May cause drowsiness, avoid driving or operating machinery until effects are known
• Use with caution in patients with heart disease or arrhythmia
• Not recommended during pregnancy unless clearly needed
• Avoid in patients with a recent heart attack
• Use cautiously in patients with a history of seizures
• May increase suicidal thoughts in young adults during early treatment
• Avoid abrupt discontinuation to prevent withdrawal symptoms

Clomfranil Tablet 25mg Side Effects

• Dry mouth
• Constipation
• Blurred vision
• Drowsiness or fatigue
• Dizziness on standing up
• Weight gain
• Sweating
• Tremor
• Rapid heartbeat
• Sexual dysfunction

Storage Conditions

• Store below 30°C in a cool, dry place
• Keep away from direct sunlight and moisture
• Keep the tablets in their original blister pack
• Keep out of reach of children
• Do not use after the expiry date printed on the pack