Clotles Plus Tablet 75mg/75mg

About Clotles Plus Tablet 75mg/75mg

Clotles Plus Uses

• Prevention of heart attack after acute coronary syndrome
• Prevention of stroke after a prior ischemic stroke or mini stroke
• Prevention of clot formation after coronary stent placement
• Peripheral arterial disease
• Secondary prevention of cardiovascular events

Clotles Plus Benefits

• Lower chance of a repeat heart attack or stroke
• Stents kept open and functioning after angioplasty
• Improved blood flow in narrowed arteries

What Experts Say

Clotles Plus combines two antiplatelet agents that act on different steps of clot formation. Aspirin blocks thromboxane A2 production so platelets clump less, while clopidogrel blocks the P2Y12 receptor on platelets so they cannot activate each other. Together they lower the chance that a clot blocks a narrowed artery.

Cardiologists prescribe this combination after a heart attack, an ischemic stroke, or placement of a coronary stent, usually for a limited period rather than for life. The dual approach cuts the risk of a repeat cardiac event more than either drug alone, though it also raises bleeding risk, so doctors set a clear stop date.

Cardiac disease is rising fast here due to smoking, unmanaged diabetes, and a diet heavy in fried and salty food, so many patients start dual antiplatelet therapy soon after a first cardiac event. Skipping doses or stopping early because symptoms feel better is a common and dangerous habit. This tablet should never be stopped without the treating cardiologist's approval, since sudden withdrawal can trigger stent blockage.

Drug Class

• Antiplatelet Combination

Clotles Plus Tablet 75mg/75mg formula

• Aspirin
• Clopidogrel

Available forms

• Tablet

How to use Clotles Plus Tablet 75mg/75mg?

• Take Clotles Plus once daily at the same time each day.
• Swallow the tablet whole with water, with or without food.
• Continue the tablet for exactly as long as the cardiologist advises.
• Do not stop the tablet suddenly without medical advice.

Drug Interactions

• Warfarin or Other Anticoagulants: Combining with Clotles Plus significantly increases bleeding risk.
• Proton Pump Inhibitors (Omeprazole): Omeprazole can reduce clopidogrel's effectiveness by interfering with its activation in the liver.
• NSAIDs (Ibuprofen, Naproxen): NSAIDs such as ibuprofen and naproxen increase the risk of stomach bleeding when taken with this combination.

Risks and warnings

• Bleeding Risk: The combination significantly raises the risk of bleeding, including from the stomach and brain.
• Before Surgery: This combination must be stopped several days before planned surgery or dental procedures under medical guidance.
• Stomach Ulcers: Aspirin can irritate the stomach lining and worsen existing ulcers.
• Sudden Discontinuation: Stopping abruptly after stent placement can cause the stent to block suddenly.

Clotles Plus Side Effects

• Easy bruising
• Nosebleeds
• Stomach upset
• Heartburn
• Prolonged bleeding from cuts
• Diarrhea
• Skin rash
• Blood in urine or stool

Storage Conditions

• Store below 30°C in a dry place.
• Keep the blister strip away from direct light and moisture.
• Do not use after the expiry date.
• Keep out of reach of children.