Co-Valid Tablet 160mg / 25mg

About Co-Valid Tablet 160mg / 25mg

Co-Valid Tablet Uses

• High blood pressure (hypertension)
• Hypertension not controlled by a single medicine
• Long term blood pressure management
• Reducing risk of stroke and heart attack linked to high blood pressure

Co-Valid Tablet Benefits

• Combines two blood pressure lowering mechanisms in one tablet
• Improves blood pressure control compared to single therapy
• Simplifies dosing with a once daily tablet
• Helps protect the heart and kidneys over the long term

What Experts Say

High blood pressure affects a large share of adults in Pakistan, often going undiagnosed for years because symptoms are mild or absent. Pakistani physicians frequently combine two medicines when a single drug fails to bring blood pressure to target levels. This tablet pairs an angiotensin receptor blocker with a diuretic to lower high blood pressure through two separate mechanisms at once.

Valsartan blocks the action of angiotensin II, a hormone that narrows blood vessels and raises pressure. Hydrochlorothiazide works differently, helping the kidneys remove excess salt and water from the body. Together these mechanisms lower blood pressure more effectively than either medicine used alone, which is why fixed dose combinations are widely prescribed.

Regular blood pressure checks and periodic blood tests are important on this combination, since it can affect kidney function and electrolyte levels. Physicians usually start with a lower strength before moving to higher doses like this one. Anyone experiencing severe dizziness, swelling or reduced urination should contact a doctor promptly.

Drug Class

• Angiotensin receptor blocker (ARB) and thiazide diuretic combination
• Antihypertensive agent

Co-Valid Tablet 160mg / 25mg formula

• Valsartan 160mg + Hydrochlorothiazide 25mg

Available forms

• Tablet

How to use Co-Valid Tablet 160mg / 25mg?

• Take one tablet daily at the same time each day.
• Swallow the tablet whole with a glass of water.
• Take it with or without food as advised by your doctor.
• Do not stop the tablet suddenly without medical advice.

Drug Interactions

• Lithium: This combination can raise lithium levels in the blood to potentially toxic amounts.
• NSAIDs: Regular use of painkillers like ibuprofen can reduce the blood pressure lowering effect and stress the kidneys.
• Potassium Supplements: May raise the risk of high blood potassium when combined with this tablet.
• Other Blood Pressure Medicines: Combining with additional antihypertensives can cause blood pressure to drop too low.

Risks and warnings

• Kidney Function: Regular monitoring is needed since this combination can affect kidney function, especially with prior kidney disease.
• Low Blood Pressure: May cause dizziness or fainting, particularly after the first dose or in dehydrated patients.
• Electrolyte Imbalance: The diuretic component can lower potassium and sodium levels, needing periodic blood tests.
• Pregnancy: Avoid use during pregnancy since it can cause serious harm to the developing baby.

Co-Valid Tablet Side Effects

• Dizziness
• Headache
• Fatigue
• Low blood pressure
• Increased urination
• Muscle cramps
• Nausea
• Electrolyte imbalance
• Increased blood sugar in rare cases
• Allergic skin reactions

Storage Conditions

• Store below 30°C in a cool, dry place away from moisture.
• Keep tablets in the original blister strip until use.
• Keep out of reach of children.
• Discard any unused tablets after the expiry date printed on the pack.