Comax tablet 80mg / 400mg

About Comax tablet 80mg / 400mg

Comax tablet 80mg / 400mg Uses

• Urinary tract infections
• Acute bronchitis and respiratory infections
• Traveler's diarrhea and certain gut infections
• Ear infections
• Pneumocystis pneumonia prevention and treatment in select patients

Drug Class

• Sulfonamide antibiotic combination
• Folate synthesis inhibitor

What Experts Say

Trimethoprim and sulfamethoxazole work together to block two separate steps bacteria use to make folate, a substance they need to grow. Combining them makes the antibiotic more effective than either drug used alone.

Comax tablet is usually taken every twelve hours, with a full glass of water, for the number of days the doctor prescribes. Drinking extra fluids during treatment helps protect the kidneys.

It is a sulfa based antibiotic, so people with a known sulfa allergy should avoid it and tell their doctor about any past drug reactions. Skin rash, especially one that spreads or blisters, needs prompt medical attention.

Comax tablet 80mg / 400mg formula

• Trimethoprim 80mg
• Sulfamethoxazole 400mg

Available forms

• Tablet

How to use Comax tablet 80mg / 400mg?

• Take one tablet every 12 hours, or as directed by the doctor.
• Swallow with a full glass of water.
• Drink plenty of fluids throughout the day during treatment.
• Complete the full course even if symptoms improve early.

Drug Interactions

Comax tablet can interact with several commonly used medicines.

• Warfarin: Significantly increases bleeding risk and warfarin levels.
• Methotrexate: Raises the risk of methotrexate toxicity and blood disorders.
• ACE inhibitors or potassium sparing diuretics: Can raise blood potassium to unsafe levels.

Risks and warnings

• Sulfa allergy: Avoid if allergic to sulfonamide medicines, since it can cause serious skin reactions.
• Blood disorders: Can rarely affect blood cell counts, especially with prolonged use.
• Kidney function: Use with caution in people with kidney disease, and stay well hydrated.
• Pregnancy: Avoid near term, since it can affect the baby's bilirubin levels.

Comax tablet 80mg / 400mg Side Effects

• Nausea
• Vomiting
• Loss of appetite
• Skin rash
• Headache
• Diarrhea

Storage Conditions

Store below 30°C in a dry place away from moisture and direct sunlight, out of reach of children.