About Deprel Tablet 100mg
Deprel Tablet 100mg contains trazodone, a SARI antidepressant used for depression and insomnia.
Deprel Tablet 100mg Uses
- Treats major depressive disorder in adults
- Helps manage anxiety symptoms that occur alongside depression
- Sometimes used at lower doses, on a doctor's advice, to treat insomnia and sleep disturbances
- May improve mood, appetite, and energy levels affected by depression
Deprel Tablet 100mg Benefits
- Works differently from SSRIs, making it a useful option when other antidepressants cause sexual side effects
- Has a calming effect that can help patients who struggle with sleep alongside depression
- Offers an affordable, locally manufactured option for long term antidepressant therapy
Drug Class
- Serotonin antagonist and reuptake inhibitor (SARI)
What Experts Say
Psychiatrists in Pakistan often prescribe Deprel Tablet 100mg when a patient's depression comes with marked sleep disturbance, since trazodone's sedating profile can address both symptoms with a single medicine. Many doctors start at a lower strength and titrate upward gradually to limit dizziness and daytime drowsiness while the body adjusts.
Because trazodone works differently from SSRIs, doctors often consider it when a patient has not tolerated first line antidepressants well, particularly with sexual side effects or persistent insomnia. Regular follow up visits let the doctor monitor blood pressure, mood, and sedation levels, especially during the first few weeks of therapy.
Given the high burden of untreated depression across the country, expert psychiatric guidance emphasizes that trazodone should never be stopped suddenly, since doing so can trigger withdrawal like symptoms and a possible return of the original depressive symptoms. A gradual, doctor supervised taper is recommended whenever therapy is being discontinued or switched to another class of antidepressant.
Deprel Tablet 100mg Uses in Urdu
- ڈپریشن (ذہنی دباؤ) کے علاج کے لیے استعمال ہوتی ہے
- ڈپریشن کے ساتھ ہونے والی گھبراہٹ اور بے چینی کم کرنے میں مددگار ہے
- نیند کی خرابی اور بے خوابی کے علاج میں مددگار ہے
- موڈ، بھوک اور توانائی کی سطح بہتر بنانے میں مدد دیتی ہے
Deprel Tablet 100mg formula
How to use Deprel Tablet 100mg?
- Take Deprel Tablet 100mg exactly as prescribed by your doctor, usually once daily in the evening or divided into two doses
- Swallow the tablet whole with a glass of water, with or without food
- Take with food if the medicine causes stomach upset or dizziness
- Do not stop the medicine suddenly without consulting your doctor, even if you feel better
- Take a missed dose as soon as remembered, unless it is close to the next scheduled dose
Drug Interactions
- MAOI Antidepressants: Must not be combined, due to a risk of serotonin syndrome.
- SSRIs, SNRIs, Or Triptans: Increases serotonin syndrome risk.
- Alcohol, Benzodiazepines, Opioids: Enhances sedation.
- Digoxin Or Phenytoin: May increase levels in the blood, requiring monitoring.
- Carbamazepine: Can reduce trazodone's effectiveness.
- Antihypertensives: Can strengthen the blood pressure lowering effect.
- Cimetidine: May raise trazodone blood levels.
Risks and warnings
- Suicidal Thoughts: May increase suicidal thoughts, especially in children, teenagers, and young adults during the first weeks of treatment.
- Priapism: Can cause a prolonged, painful erection in men, a medical emergency requiring immediate attention.
- Drowsiness: May cause drowsiness and dizziness, avoid driving or operating machinery until effects are known.
- Orthostatic Hypotension: Can lower blood pressure suddenly on standing up, increasing fall risk in elderly patients.
- Heart Disease: Use with caution, since trazodone can affect heart rhythm.
- Alcohol: Avoid while taking this medicine, as it increases sedation and other side effects.
- Pregnancy: Not recommended unless clearly necessary, caution advised during breastfeeding.
- Liver Or Kidney Impairment: Use cautiously, dose adjustment may be required.
Deprel Tablet 100mg Side Effects
- Drowsiness and daytime sleepiness
- Dizziness or lightheadedness
- Dry mouth
- Blurred vision
- Headache
- Nausea or vomiting
- Low blood pressure on standing up
- Constipation
- Weight changes
- Priapism (rare but serious, requires urgent medical care)
Storage Conditions
- Store below 30°C in a cool, dry place
- Keep away from direct sunlight and moisture
- Keep the tablet strip in its original packaging until use
- Store out of reach of children
- Do not use after the expiry date printed on the pack
