Deprogesic-P Tablet 37.5mg/325mg

About Deprogesic-P Tablet 37.5mg/325mg

Deprogesic-P Tablet Uses

• Moderate to moderately severe pain
• Post surgical pain
• Pain after dental procedures
• Musculoskeletal pain, including back and joint pain
• Pain from injuries such as sprains or fractures

Deprogesic-P Tablet Benefits

• A combination of two pain relief mechanisms for a stronger effect than either drug alone
• Faster relief than paracetamol alone for moderate pain
• A lower opioid dose than tramadol used by itself, since paracetamol shares the workload
• Suitable for short term pain control after common procedures

What Experts Say

Pain specialists describe this combination as a balanced option for pain that plain paracetamol cannot control. Tramadol acts on the brain's pain signals while paracetamol adds a separate pain relieving and fever reducing effect. Together they often work better than either medicine alone. This approach can also allow a lower opioid dose than tramadol used alone.

Doctors typically prescribe this tablet for short courses rather than continuous long term use. The opioid component can lead to tolerance and dependence if taken for extended periods. Most guidelines recommend the lowest effective dose for the shortest possible time. Regular reassessment helps confirm that ongoing use is still necessary.

Physicians also stress caution in people with a history of seizures or breathing problems. Combining this medicine with alcohol, sedatives or other opioids raises the risk of dangerous drowsiness. Older adults and those with liver or kidney disease usually need a lower, carefully monitored dose. A gradual dose reduction is generally preferred over stopping suddenly after prolonged use.

Drug Class

• Opioid Analgesic Combination
• Centrally Acting Pain Reliever

Deprogesic-P Tablet 37.5mg/325mg formula

• Tramadol Hydrochloride 37.5mg
• Paracetamol 325mg

Available forms

• Tablet

How to use Deprogesic-P Tablet 37.5mg/325mg?

• This tablet is usually taken with a full glass of water, with or without food.
• The prescribed dose and spacing between doses should not be changed without a doctor's advice.
• Crushing or chewing the tablet is not recommended, since it should be swallowed whole.
• Alcohol is best avoided while this medicine is being used, since it adds to drowsiness.
• A missed dose is generally skipped if it is almost time for the next one, without doubling up.

Drug Interactions

• MAO Inhibitors: Taking this tablet with MAO inhibitors can cause a dangerous rise in serotonin activity.
• SSRIs and SNRIs: Combined use with these antidepressants increases the risk of serotonin syndrome.
• Alcohol and Sedatives: These combinations add to drowsiness and can slow breathing to unsafe levels.
• Other Opioid Pain Relievers: Using multiple opioids together raises the risk of respiratory depression and overdose.
• Warfarin: Tramadol can increase the blood thinning effect of warfarin, raising bleeding risk.
• Other Paracetamol Containing Products: Taking additional paracetamol products alongside this tablet raises the risk of liver damage.

Risks and warnings

• Seizure Risk: Tramadol can lower the seizure threshold, so caution is needed in people with epilepsy or a seizure history.
• Respiratory Depression: High doses or combination with other sedatives can slow breathing to a dangerous level.
• Liver Function: The paracetamol component can harm the liver if the maximum daily dose is exceeded or combined with alcohol.
• Dependence: Extended use of the tramadol component can lead to tolerance and physical dependence.
• Serotonin Syndrome: Combining this tablet with antidepressants or other serotonin affecting drugs raises the risk of serotonin syndrome.

Deprogesic-P Tablet Side Effects

Some side effects are common, especially when starting this medicine.

• Nausea or vomiting
• Dizziness or drowsiness
• Constipation
• Dry mouth
• Sweating

Other effects are less common but need urgent medical attention.

• Difficulty breathing or shallow breathing
• Seizures or convulsions
• Signs of liver problems, such as yellowing skin or dark urine
• Severe allergic reactions, including swelling of the face or throat

Storage Conditions

• Store this medicine at room temperature, away from moisture and direct heat.
• Keep the strip in its original packaging until it is time to take a dose.
• Keep this medicine out of reach of children, since an overdose can be dangerous.
• Dispose of any unused or expired tablets safely rather than keeping them at home.