Dermazin Cream 0.01 50g

About Dermazin Cream 0.01 50g

Dermazin Cream Uses

• Infection prevention in second and third degree burns
• Care for skin graft donor sites
• Treatment of infected leg ulcers and pressure sores
• Management of minor infected wounds and cuts

Dermazin Cream Benefits

• Broad antibacterial action against common wound pathogens
• A soothing base that keeps the wound moist for healing
• Lower risk of infection spreading to deeper tissue
• Suitability for use under medical supervision in burn care

What Experts Say

Silver sulfadiazine combines the antibacterial action of a sulfonamide with the antimicrobial effect of silver ions. Together these disrupt bacterial cell walls and interfere with DNA replication, giving the cream activity against a wide range of bacteria and some fungi that commonly infect burns and wounds.

In Pakistan, burn injuries from cooking accidents, hot liquids and stove related mishaps are common, and this cream is widely used in emergency departments and outpatient wound care clinics. Pakistani physicians often recommend it as a first line topical treatment once a burn or wound has been properly cleaned and assessed.

Because silver sulfadiazine can be absorbed through large or extensively burned areas, doctors monitor patients with major burns for changes in blood counts and kidney function. It is generally avoided in newborns and late pregnancy due to a small risk of jaundice in the baby.

Drug Class

• Topical antibacterial
• Sulfonamide derivative

Dermazin Cream 0.01 50g formula

• Silver Sulfadiazine 1%

Available forms

• Cream

How to use Dermazin Cream 0.01 50g?

• A clean, dry wound surface helps Dermazin Cream work effectively.
• A thin layer, about 3 to 5mm thick, is usually applied once or twice daily.
• A sterile dressing over the area may be advised by your doctor.
• Reapplication after bathing or dressing changes is often needed.
• The full course length recommended by your doctor should be completed.

Drug Interactions

• Silver Salts: Other silver containing products used together may increase the risk of skin discoloration.
• Enzymatic Debriding Agents: Silver sulfadiazine can reduce the effectiveness of enzyme based wound debridement products.
• Oral Sulfonylureas: A theoretical risk of increased blood sugar lowering effect exists with absorbed sulfadiazine.
• Cimetidine: The risk of low white blood cell counts increases when used with silver sulfadiazine.

Risks and warnings

• Sulfa Allergy: A known allergy to sulfa drugs means this cream should be avoided, since it may trigger a serious skin reaction.
• Newborn Caution: Premature babies and infants under two months face a risk of jaundice with this cream.
• Kidney or Liver Disease: Caution is needed since silver sulfadiazine can be absorbed through large wound areas.
• Pregnancy: Use near the end of pregnancy and during breastfeeding should be avoided unless a doctor advises otherwise.
• Large Burn Areas: Extensive application over large burned areas needs close medical monitoring for absorption effects.

Dermazin Cream Side Effects

• Burning or stinging on application
• Itching at the application site
• Skin rash
• Bluish gray discoloration of the skin
• Temporary reduction in white blood cell count
• Allergic reactions such as swelling or difficulty breathing in rare cases

Storage Conditions

• Store the tube or jar below 25°C away from direct heat.
• Keep the container tightly closed after each use.
• Avoid freezing the cream.
• Keep away from direct sunlight.
• Keep out of reach of children.