About Dimis Tablet 75mg / 0.2mg
Combination NSAID and prostaglandin tablet for arthritis pain with reduced ulcer risk.
Dimis Tablet 75mg / 0.2mg Uses
- Osteoarthritis pain and joint stiffness
- Rheumatoid arthritis pain and swelling
- Long term NSAID therapy in patients at high risk of stomach or duodenal ulcers
Dimis Tablet 75mg / 0.2mg Benefits
- Eases joint pain, swelling and morning stiffness
- Lowers the risk of NSAID induced gastric and duodenal ulcers
- Allows continued arthritis treatment without stopping NSAID therapy
- Combines pain relief and stomach protection in a single tablet
What Experts Say
Diclofenac Sodium is an NSAID that blocks cyclooxygenase-1 and cyclooxygenase-2 enzymes to cut prostaglandin production in inflamed joint tissue. This lowers pain, swelling and morning stiffness in patients living with osteoarthritis and rheumatoid arthritis, making daily movement noticeably easier for most users.
Misoprostol is a synthetic prostaglandin E1 analogue that protects the stomach lining by boosting mucus and bicarbonate secretion while lowering gastric acid output. This mechanism directly offsets the ulcer risk that long term NSAID therapy is known to carry in the digestive tract over time.
Combining both actives in one tablet lets patients who need regular NSAID treatment continue therapy with a meaningfully lower chance of gastric or duodenal ulceration compared to diclofenac taken alone, which is why rheumatology guidance favors this pairing for high risk arthritis patients in Pakistan.
Drug Class
- NSAID (Nonsteroidal Anti Inflammatory Drug) combined with a Prostaglandin E1 Analogue
Dimis Tablet 75mg / 0.2mg Uses in Urdu
- اوسٹیوآرتھرائٹس کے درد اور جوڑوں کی اکڑن میں
- رمیٹائیڈ آرتھرائٹس کے درد اور سوجن میں
- طویل المدت NSAID ادویات کے استعمال سے معدے کے زخم سے بچاؤ کے لیے
Dimis Tablet 75mg / 0.2mg formula
- Diclofenac Sodium 75mg + Misoprostol 200mcg
How to use Dimis Tablet 75mg / 0.2mg?
- Take Dimis Tablet exactly as prescribed by the doctor, usually two to four times daily
- Swallow the tablet whole with a full glass of water, do not crush or chew it
- Take with food or milk to reduce stomach upset
- Avoid magnesium containing antacids at the same time, as they can worsen diarrhea
- Do not stop the medicine suddenly without consulting the doctor
Drug Interactions
- ACE Inhibitors and ARBs: Dimis Tablet can reduce the blood pressure lowering effect of these medicines and add to kidney strain
- Warfarin and Other Blood Thinners: Combined use raises the risk of serious gastrointestinal bleeding
- Lithium: Diclofenac Sodium can raise lithium blood levels, increasing the risk of toxicity
- Methotrexate: Concurrent use may increase methotrexate toxicity
- Diuretics: Effectiveness may be reduced, and kidney function should be monitored
- Other NSAIDs or Aspirin: Taking together increases the risk of stomach bleeding without added benefit
- Magnesium Containing Antacids: These can worsen the diarrhea caused by Misoprostol
Risks and warnings
- Pregnancy Warning: Dimis Tablet must not be used during pregnancy, as Misoprostol can cause miscarriage, premature labor or birth defects
- Cardiovascular Risk: NSAIDs like Diclofenac Sodium can raise the risk of heart attack and stroke, especially with long term use
- Gastrointestinal Bleeding: Serious stomach bleeding, ulceration or perforation can occur even without warning symptoms
- Kidney Function: Long term use may reduce kidney function, particularly in older adults or those with existing kidney disease
- Liver Function: Liver enzyme levels should be monitored during extended treatment
- Asthma Caution: Patients with aspirin sensitive asthma should avoid this medicine due to the risk of severe allergic reaction
Dimis Tablet 75mg / 0.2mg Side Effects
- Diarrhea and abdominal cramping
- Nausea and indigestion
- Headache and dizziness
- Flatulence and bloating
- Skin rash or itching
- Fluid retention and mild swelling
- Black or tarry stools (serious, needs immediate medical attention)
- Chest pain or shortness of breath (serious, needs immediate medical attention)
- Yellowing of the skin or eyes (serious, needs immediate medical attention)
- Severe skin blistering or peeling (serious, needs immediate medical attention)
Storage Conditions
- Store below 30°C in a cool, dry place
- Protect from direct heat, light and moisture
- Keep the tablet in its original blister pack until the dose is due
- Keep out of reach of children
