Divestra Tablet 2mg/35mcg

About Divestra Tablet 2mg/35mcg

Divestra Tablet 2mg/35mcg Uses

• Treats moderate to severe acne in women that has not improved with other treatments
• Reduces excess facial and body hair growth linked to high androgen levels
• Regulates irregular or heavy menstrual cycles
• Works as a reliable oral contraceptive when taken correctly

Divestra Tablet 2mg/35mcg Benefits

• Combines an anti-androgen with estrogen to control hormone driven skin and hair symptoms
• Improves acne and oily skin with a few months of regular use
• Offers predictable, reversible contraception
• Helps make menstrual cycles more regular

Drug Class

• Combined hormonal contraceptive
• Anti-androgen and estrogen combination

What Experts Say

Cyproterone acetate blocks androgen receptors in the skin, which lowers oil production and acne severity over time. Ethinylestradiol, a synthetic estrogen, works alongside it to suppress ovulation and stabilize the menstrual cycle. Together the two hormones give Divestra both an anti-acne and a contraceptive effect.

Studies on cyproterone acetate and ethinylestradiol combinations show clear improvement in acne and hirsutism after three to six cycles of use, though full benefit takes time to appear. The same hormonal action that treats acne also raises the risk of blood clots, so doctors reserve this tablet for women who genuinely need both the skin benefit and contraception, not acne alone.

Because estrogen containing tablets carry a higher clotting risk in smokers and women over 35, clinicians in Pakistan generally screen blood pressure, clotting history and smoking status before prescribing Divestra. Regular follow up helps balance its hormonal benefits against these cardiovascular risks.

Divestra Tablet 2mg/35mcg formula

• Cyproterone Acetate + Ethinylestradiol

Available forms

• Tablet

How to use Divestra Tablet 2mg/35mcg?

• Take one tablet daily at the same time for 21 days
• Follow with a 7 day tablet free break before starting the next strip
• Start the first tablet on day one of your menstrual cycle unless your doctor advises otherwise
• Use an extra contraceptive method for the first 7 days if starting mid cycle

Drug Interactions

• Enzyme Inducing Anti Seizure Drugs: Phenytoin, carbamazepine and similar drugs can lower Divestra's contraceptive effect
• Rifampicin And Griseofulvin: These reduce hormone levels and may cause breakthrough bleeding or reduced protection
• St John's Wort: This herbal supplement can lower the effectiveness of the tablet
• HIV Or Hepatitis C Protease Inhibitors: May change hormone levels and require an alternate contraceptive plan

Risks and warnings

• Blood Clot Risk: Raises the chance of deep vein thrombosis, pulmonary embolism, stroke or heart attack
• Smoking: Significantly increases clot risk, especially in women over 35
• Migraine With Aura: Avoid use due to a higher stroke risk
• Liver Disease: Not recommended in active liver disease or liver tumors
• Pregnancy: Not to be used during pregnancy or breastfeeding

Divestra Tablet 2mg/35mcg Side Effects

• Nausea and abdominal discomfort
• Headache
• Breast tenderness
• Mood changes
• Weight gain or fluid retention
• Reduced sex drive
• Breakthrough spotting between periods
• Signs of blood clots such as leg swelling, chest pain or sudden vision changes need urgent medical attention

Storage Conditions

• Store below 30°C in a dry place away from direct light
• Keep each tablet in its blister strip until the dose is due
• Keep out of reach of children
• Do not use after the expiry date on the pack