E-Clar DS Tablet 500mg

About E-Clar DS Tablet 500mg

E-Clar DS Tablet 500mg Uses

• Respiratory tract infections such as bronchitis and pneumonia
• Sinus infections
• Throat infections
• Skin and soft tissue infections
• Combination therapy for stomach ulcers linked to H. pylori bacteria

E-Clar DS Tablet 500mg Benefits

• Broad coverage against many common respiratory pathogens
• Reaches high concentrations in lung and sinus tissue
• Twice daily dosing improves convenience compared to some antibiotics
• Often used as part of proven H. pylori eradication regimens

What Experts Say

Clarithromycin is a macrolide antibiotic that stops bacteria from producing the proteins they need to survive by binding to their ribosomes. This makes it effective against many of the organisms responsible for community acquired respiratory infections.

Physicians frequently choose clarithromycin for patients with a penicillin allergy who need coverage for a respiratory or skin infection, since the drug offers a similar spectrum through a different mechanism. It is also a standard component of combination therapy used to eradicate the bacteria linked to peptic ulcer disease.

Because clarithromycin strongly affects certain liver enzymes, doctors routinely review a patient's other medicines, particularly cholesterol lowering statins and blood thinners, before starting treatment. Pakistan's high burden of respiratory infections and H. pylori related ulcer disease keeps this antibiotic in steady clinical demand.

Drug Class

• Macrolide Antibiotic

E-Clar DS Tablet 500mg formula

• Clarithromycin

Available forms

• Tablet

How to use E-Clar DS Tablet 500mg?

• Take the tablet with or without food as advised.
• Swallow whole with a glass of water, do not crush unless instructed.
• Space doses evenly through the day as prescribed.
• Complete the full course even if symptoms improve early.
• Avoid taking within two hours of certain antacid medicines unless advised otherwise.

Drug Interactions

• Statins: Clarithromycin can raise blood levels of simvastatin and atorvastatin, increasing the risk of muscle damage.
• Warfarin: May significantly increase bleeding risk by raising warfarin levels.
• Digoxin: Levels of this heart medicine can rise to potentially toxic amounts.
• Colchicine: Combined use can lead to serious colchicine toxicity, especially in people with kidney or liver problems.
• Ergot Alkaloids: Increases the risk of severe blood vessel narrowing when combined with certain migraine medicines.

Risks and warnings

• Heart Rhythm Conditions: Avoid in people with a known prolonged QT interval or certain heart rhythm disorders.
• Liver Disease: Use with caution since the drug is processed by the liver and can rarely cause liver injury.
• Kidney Disease: The dose may need to be reduced in significant kidney impairment.
• Macrolide Allergy: Avoid if there is a known allergy to clarithromycin, erythromycin, or related antibiotics.
• Pregnancy: Use only if clearly needed and advised by a doctor.

E-Clar DS Tablet 500mg Side Effects

• Nausea or vomiting
• Diarrhea
• Abdominal pain
• A metallic or unusual taste in the mouth
• Headache
• Skin rash
• Rare liver enzyme changes
• Rare heart rhythm changes in susceptible individuals

Storage Conditions

• Store below 25°C in a cool, dry place.
• Keep the strip in its original packaging away from moisture.
• Protect from direct sunlight.
• Keep out of reach of children.
• Discard any leftover tablets after finishing the prescribed course.