E-Clar Tablet 250mg

About E-Clar Tablet 250mg

E-Clar Tablet Uses

• Treats respiratory tract infections such as bronchitis and pneumonia
• Treats throat and sinus infections
• Treats skin and soft tissue infections
• Used in combination therapy for stomach ulcers linked to H. pylori
• Treats certain ear infections

E-Clar Tablet Benefits

• Broad spectrum activity against common respiratory and skin pathogens
• Twice daily dosing supports easier treatment adherence
• Effective against some bacteria resistant to penicillin
• Well absorbed when taken with or without food

What Experts Say

Clarithromycin belongs to the macrolide class of antibiotics. It works by binding to the bacterial ribosome and blocking protein synthesis, which stops bacteria from multiplying and allows the immune system to clear the infection.

This mechanism makes it effective against many gram positive organisms and several atypical bacteria that cause respiratory infections, including strains that do not respond well to penicillin based antibiotics. It also has activity against Helicobacter pylori, which is why it is sometimes combined with other agents for ulcer treatment.

Clinicians monitor cardiac history before prescribing clarithromycin because macrolides can prolong the QT interval in susceptible individuals, especially when combined with other QT prolonging drugs. Drug interaction screening is also important since clarithromycin inhibits liver enzymes that metabolize several other common medications, raising the risk of toxicity if not adjusted.

Drug Class

• Macrolide Antibiotic

E-Clar Tablet 250mg formula

• Clarithromycin

Available forms

• Tablet (250mg)

How to use E-Clar Tablet 250mg?

• Take the tablet with a full glass of water, with or without food.
• Swallow the tablet whole. Do not crush or chew it.
• Take doses about 12 hours apart to maintain steady drug levels.
• Complete the full course as prescribed, even if symptoms improve early.
• Take at the same times each day to avoid missed doses.

Drug Interactions

• Statins: Increases blood levels of certain statins, raising the risk of muscle damage.
• Warfarin: May enhance the blood thinning effect and raise bleeding risk.
• QT Prolonging Drugs: Combining with other drugs that prolong the QT interval raises the risk of dangerous heart rhythm changes.
• Colchicine: Increases colchicine levels and toxicity risk, especially in people with kidney or liver impairment.

Risks and warnings

• Heart Rhythm Conditions: Use with caution in people with a history of QT prolongation or irregular heartbeat.
• Liver Disease: Dose adjustment may be needed in people with significant liver impairment.
• Kidney Disease: Reduced dosing may be required in people with severe kidney impairment.
• Pregnancy: Use only if clearly needed and under a doctor's supervision, as safety in pregnancy is not fully established.
• Drug Interactions: Inform the doctor about all current medications before starting treatment, since clarithromycin interacts with several common drugs.

E-Clar Tablet 250mg Side Effects

• Nausea or vomiting
• Diarrhea or abdominal discomfort
• Altered or metallic taste in the mouth
• Headache
• Skin rash
• Irregular heartbeat (rare, seek medical attention)
• Liver enzyme changes on lab tests

Storage Conditions

• Store below 25°C in a cool, dry place.
• Keep away from direct sunlight and moisture.
• Keep out of reach of children.
• Discard any unused tablets after the expiry date.