Erwin Tablet 75mg/0.2mg

About Erwin Tablet 75mg/0.2mg

Erwin Tablet 75mg/0.2mg Uses

• Osteoarthritis pain and stiffness
• Rheumatoid arthritis pain and inflammation
• Long term NSAID therapy in patients with a high risk of stomach ulcers
• Prevention of NSAID induced gastric and duodenal ulcers

What Experts Say

Erwin Tablet 75mg/0.2mg combines two active ingredients with opposite but complementary roles. Diclofenac sodium is a nonsteroidal anti-inflammatory drug that blocks the enzymes responsible for pain and swelling in arthritis. Misoprostol is a prostaglandin analogue that protects the stomach lining, which NSAIDs otherwise expose to acid damage over time.

This fixed dose combination exists specifically for patients who need ongoing NSAID treatment for chronic joint pain but also carry a higher risk of gastric or duodenal ulcers, such as older adults or those with a prior ulcer history. Pairing the two ingredients in one tablet reduces the number of pills a patient must take and supports treatment adherence.

Misoprostol also stimulates uterine contractions, which is why this combination carries a strict pregnancy warning and is never prescribed to women who are or may become pregnant. Regular monitoring of kidney function and blood pressure is advised during long term use, since the diclofenac component carries the same cardiovascular and kidney related cautions as other NSAIDs.

Drug Class

• NSAID and prostaglandin analogue combination

Erwin Tablet 75mg/0.2mg formula

• Diclofenac Sodium 75mg + Misoprostol 0.2mg

Available forms

• Tablet

How to use Erwin Tablet 75mg/0.2mg?

• Take one Erwin tablet with food, usually two to four times daily as prescribed by your doctor.
• Swallow the tablet whole with a full glass of water.
• Do not take this medicine if you are pregnant or planning pregnancy.
• Use a reliable form of contraception while taking this medicine if you can become pregnant.
• Do not stop or adjust the dose without your doctor's advice.

Drug Interactions

• Blood thinners (Warfarin): Increases the risk of bleeding when combined with the diclofenac component.
• Other NSAIDs or Aspirin: Raises the risk of stomach ulcers and bleeding, avoid combining.
• ACE inhibitors or ARBs: Diclofenac can reduce their blood pressure lowering effect and affect kidney function.
• Diuretics: Combined use may reduce the diuretic effect and strain the kidneys.
• Magnesium containing antacids: May worsen misoprostol related diarrhea.
• Corticosteroids: Increases the risk of stomach irritation and bleeding.

Risks and warnings

• Pregnancy: Strictly contraindicated. Misoprostol can cause uterine contractions, bleeding, and miscarriage, and must never be used during pregnancy.
• Women of childbearing age: A negative pregnancy test and reliable contraception are required before starting treatment.
• Stomach bleeding: Long term NSAID use can still cause ulcers or bleeding even with misoprostol protection.
• Kidney function: Use with caution in people with existing kidney disease or dehydration.
• Heart risk: Long term NSAID use may raise the risk of heart attack or stroke.
• Breastfeeding: Not recommended, since misoprostol can pass into breast milk.

Erwin Tablet 75mg/0.2mg Side Effects

Side effects can involve both the digestive system and the diclofenac component.

• Diarrhea, often the most common effect from misoprostol
• Abdominal pain or cramping
• Nausea
• Indigestion or heartburn
• Headache
• Dizziness
• Skin rash
• Heavy vaginal bleeding or severe abdominal pain: seek immediate medical care, especially if pregnancy is suspected.

Storage Conditions

Store below 30°C in a cool, dry place, away from moisture and direct sunlight. Keep out of reach of children.