Floc Capsule 150mg

About Floc Capsule 150mg

Floc Capsule 150mg Uses

• Single dose treatment of vaginal candidiasis, commonly called vaginal thrush or yeast infection
• Oral and throat candidiasis, including denture related thrush and oesophageal candidiasis
• Fungal skin infections such as ringworm of the body, jock itch, athlete's foot and pityriasis versicolor
• Candidal balanitis affecting the head of the penis in male partners
• Fungal nail and scalp infections when a doctor prescribes a longer weekly course
• Prevention and treatment of systemic fungal infection in patients with weak immunity

Floc Capsule 150mg Benefits

• One capsule is often enough for a simple vaginal yeast infection, so treatment is easy to complete
• Almost fully absorbed after swallowing, which gives the same result whether taken with food or empty stomach
• Long duration of action keeps antifungal levels in tissue for several days after a single dose
• Reaches vaginal fluid, skin, saliva and spinal fluid well, so it covers infections creams cannot reach
• Avoids the mess and daily routine of vaginal pessaries and antifungal creams
• Widely available and affordable across Pakistani pharmacies as a locally made brand

What Experts Say

Fluconazole works by blocking the fungal enzyme lanosterol 14 alpha demethylase, which stops ergosterol production and leaves the fungal cell membrane leaky and unstable. The effect is fungistatic against most Candida species, so the body's own immune response still clears the remaining organisms.

A single 150mg capsule clears uncomplicated vaginal candidiasis because fluconazole has a half-life of about 30 hours and concentrates well in vaginal tissue. Doctors across Pakistan often repeat the dose after 72 hours when symptoms are severe, and move to weekly dosing in recurrent cases. Skin, scalp and nail infections need longer weekly courses.

Liver function is usually checked before prolonged courses, since raised transaminases remain the most common laboratory abnormality. Kidney function matters too, because most of the drug leaves the body unchanged in urine and doses are reduced in renal impairment. Pakistan carries a high burden of uncontrolled diabetes, and repeated candidiasis in such patients often reflects poor sugar control rather than antifungal failure.

Drug Class

• Triazole antifungal
• Systemic antifungal agent
• Ergosterol synthesis inhibitor

Floc Capsule 150mg formula

• Fluconazole 150mg

Available forms

• Capsule

How to use Floc Capsule 150mg?

• Swallow the capsule whole with a glass of water, with or without food, at any convenient time of day
• For an uncomplicated vaginal yeast infection, adults usually take one 150mg capsule as a single dose
• Your doctor may advise a second capsule 72 hours later if itching and discharge are severe or slow to settle
• Male partners with candidal balanitis are often given the same single 150mg dose to prevent reinfection
• For skin, scalp or nail fungal infections, take one capsule once weekly for as many weeks as prescribed
• Complete the full course even after symptoms improve, because stopping early allows the infection to return
• If a weekly dose is missed, take it as soon as you remember and never double up to catch up

Drug Interactions

• Warfarin and blood thinners: Fluconazole increases their effect and raises the risk of bruising and bleeding.
• Sulfonylureas such as glimepiride and gliclazide: Blood sugar can drop too low because these tablets are cleared more slowly.
• Statins such as simvastatin and atorvastatin: Levels rise and muscle pain or muscle damage becomes more likely.
• Rifampicin: It speeds up removal of fluconazole and can make the antifungal course fail.
• QT prolonging medicines such as erythromycin, amiodarone and some antipsychotics: Combined use increases the chance of a dangerous heart rhythm.
• Phenytoin, ciclosporin and tacrolimus: Blood levels of these narrow margin drugs rise and need monitoring.

Risks and warnings

• Liver problems: Fluconazole can raise liver enzymes, so tell your doctor if you have hepatitis or notice yellow eyes, dark urine or ongoing nausea.
• Kidney impairment: Most of the drug is cleared by the kidneys, so reduced doses are needed when kidney function is poor.
• Heart rhythm: The drug can lengthen the QT interval, which matters in people with known arrhythmia or low potassium and magnesium levels.
• Pregnancy: Repeated or high dose use in pregnancy is linked with birth defects, so use only if a doctor considers it clearly necessary.
• Breastfeeding: Fluconazole passes into breast milk in small amounts, so seek medical advice before taking it while nursing.
• Skin reactions: Stop the capsule and get urgent help if a spreading rash, blistering or peeling of the skin appears.
• Recurrent infection: Yeast infections that keep returning may point to uncontrolled diabetes or another underlying problem that needs testing.
• Self medication: Vaginal discharge has many causes, so confirm the diagnosis with a doctor rather than repeating the capsule on your own.

Floc Capsule 150mg Side Effects

• Headache, which is the most frequently reported effect after a single dose
• Nausea and a mild upset stomach
• Abdominal pain or cramping
• Diarrhoea or loose stools
• Indigestion and bloating
• Altered or metallic taste in the mouth
• Dizziness or a light headed feeling
• Skin rash and itching
• Hair thinning with long high dose courses
• Raised liver enzymes on blood tests
• Low potassium levels during prolonged therapy
• Rare severe skin blistering or an allergic reaction with swelling and breathing difficulty

Storage Conditions

• Store the capsule below 30 degrees Celsius in a dry place away from direct sunlight
• Keep the capsule sealed inside its original blister until the moment you take it, because moisture softens the shell
• Avoid bathroom shelves and kitchen cabinets where steam and heat collect
• Keep the blister out of sight and reach of children
• Do not use a capsule that is cracked, discoloured or past the expiry date printed on the blister