Flucon Suspension 50mg/5ml

About Flucon Suspension 50mg/5ml

Flucon Suspension 50mg/5ml Uses

• Oral and oropharyngeal thrush (fungal infection of the mouth and throat)
• Esophageal candidiasis (fungal infection of the food pipe)
• Vaginal yeast infections
• Systemic candidiasis affecting the bloodstream and internal organs
• Cryptococcal meningitis, including maintenance therapy after initial treatment
• Fungal skin infections such as ringworm and athlete's foot
• Prevention of fungal infections in patients with weakened immunity, such as those on chemotherapy

Flucon Suspension 50mg/5ml Benefits

• Once daily dosing improves compliance in children and adults alike
• Liquid form is easier to give to infants and young children who cannot swallow capsules
• Weight based dosing allows precise adjustment for pediatric patients
• Broad spectrum activity covers most common Candida and Cryptococcus species
• Good oral absorption means effects are similar to an injectable dose

What Experts Say

Fluconazole works by blocking an enzyme fungal cells need to build their outer membrane. Without this enzyme, the fungal cell wall becomes weak and leaky, and the organism eventually dies. Because human cells do not rely on this same enzyme in the same way, fluconazole is generally well tolerated at standard doses.

In children, dosing is calculated by body weight rather than a fixed amount, which is why the suspension form is preferred over tablets for younger patients. A typical starting dose ranges from 3 to 12 mg per kg once daily, depending on the type and severity of the fungal infection being treated. The oral suspension allows more accurate weight based measurement in infants and toddlers who cannot swallow capsules.

Because fluconazole is cleared mainly through the kidneys, children with reduced kidney function may need a lower dose or longer interval between doses. Doctors also watch for changes in liver enzymes and heart rhythm during longer treatment courses, and they generally prescribe the shortest duration that clears the infection effectively.

Drug Class

• Triazole antifungal
• CYP450 enzyme inhibitor class of action

Flucon Suspension 50mg/5ml formula

• Fluconazole

Available forms

• Suspension

How to use Flucon Suspension 50mg/5ml?

• Shake the bottle well before each use so the medicine mixes evenly.
• Use the measuring cup or oral syringe provided with the pack for an accurate dose.
• Give the dose at the same time each day, with or without food.
• Follow the dose set by the pediatrician based on the child's body weight and the type of infection.
• Complete the full course even if symptoms improve within a few days.
• Do not mix the suspension with other liquids or medicines unless the doctor advises it.

Drug Interactions

• Warfarin: Fluconazole inhibits the enzyme that breaks down warfarin, raising bleeding risk.
• Statins: Combined use with simvastatin or atorvastatin increases the risk of muscle toxicity.
• Oral Hypoglycemics: Fluconazole can strengthen the blood sugar lowering effect of drugs like glibenclamide, raising hypoglycemia risk.
• Phenytoin: Fluconazole raises phenytoin blood levels, increasing the risk of toxicity.
• Rifampin: Rifampin lowers fluconazole blood levels, reducing its effectiveness.
• Midazolam And Similar Sedatives: Fluconazole raises sedative blood levels, prolonging their effect.

Risks and warnings

• Liver Function: Use with caution in patients with existing liver disease, as fluconazole can raise liver enzymes.
• Heart Rhythm: Avoid in patients with a history of QT prolongation or irregular heartbeat due to a rare risk of arrhythmia.
• Pregnancy: High or repeated doses have been linked to birth defects, so use only if clearly prescribed by a doctor.
• Kidney Impairment: Dose adjustment is required in children and adults with reduced kidney function.
• Allergy: Avoid in patients with known hypersensitivity to fluconazole or other azole antifungals.

Flucon Suspension 50mg/5ml Side Effects

• Nausea
• Vomiting
• Diarrhea
• Abdominal pain
• Headache
• Skin rash
• Dizziness
• Altered taste
• Elevated liver enzymes
• Irregular heartbeat
• Severe allergic reaction with swelling or difficulty breathing
• Severe skin reactions such as blistering or peeling

Storage Conditions

• Store below 25°C in a cool, dry place away from direct sunlight.
• Keep the bottle tightly closed when not in use.
• Shake well before every dose.
• Discard the reconstituted suspension after 14 days.
• Keep out of reach of children.