Gpride-MSR Tablet 1mg/500mg

About Gpride-MSR Tablet 1mg/500mg

Drug Class

• Oral antidiabetic combination, sulfonylurea plus biguanide

• Type 2 diabetes mellitus not controlled by metformin alone
• Blood sugar management when diet and exercise are not enough
• Combination therapy in place of taking Glimepiride and Metformin as two separate tablets
• Long term glycemic control alongside a diabetic diet plan

What Experts Say

Gpride-MSR combines two medicines that work differently but complement each other. Glimepiride pushes the pancreas to release more insulin, while Metformin reduces the amount of sugar the liver produces and helps muscle and fat cells use insulin more effectively, together giving broader blood sugar control than either medicine alone.

Doctors often prescribe this combination when metformin alone no longer keeps blood sugar in a healthy range. Taking both medicines in one tablet also makes it easier for patients to stay consistent with treatment instead of managing two separate prescriptions with different dosing schedules and pill counts.

Regular blood sugar monitoring is important with this combination, since Glimepiride can lower blood sugar too much if meals are skipped or delayed. Kidney function is usually checked periodically as well, because Metformin needs adequate kidney function to be cleared safely from the body.

Gpride-MSR Tablet 1mg/500mg formula

• Glimepiride 1mg + Metformin Hydrochloride 500mg

Available forms

• Tablet

How to use Gpride-MSR Tablet 1mg/500mg?

• Take this tablet with breakfast or the first main meal of the day, unless your doctor advises otherwise.
• Swallow the tablet whole with a glass of water, do not crush or chew it.
• Take it at the same time each day to maintain steady blood sugar control.
• Do not skip meals after taking this medicine, as it can cause low blood sugar.
• Continue taking it regularly even if you feel well, unless your doctor tells you to stop.

Drug Interactions

• Insulin or other diabetes medicines: Combined use raises the risk of low blood sugar.
• Alcohol: Increases the risk of low blood sugar and lactic acidosis.
• Beta blockers: Can mask the warning signs of low blood sugar such as a fast heartbeat.
• Corticosteroids: May raise blood sugar levels and reduce this medicine's effectiveness.
• Iodinated contrast dye: May need temporary discontinuation around imaging procedures to protect kidney function.
• NSAIDs like aspirin: Can increase the blood sugar lowering effect of Glimepiride.

Risks and warnings

• Low blood sugar: Skipping meals, excess alcohol or extra physical activity can trigger hypoglycemia.
• Kidney impairment: Not recommended for patients with reduced kidney function due to the Metformin component.
• Lactic acidosis: A rare but serious risk with Metformin, more likely in patients with kidney, liver or heart failure.
• Contrast dye procedures: This medicine may need to be paused before and after imaging tests that use iodinated contrast dye.
• Pregnancy and breastfeeding: Not generally recommended, insulin is usually preferred for blood sugar control.
• Alcohol use: Increases the risk of both low blood sugar and lactic acidosis when combined with this medicine.

Gpride-MSR Tablet Side Effects

• Nausea or upset stomach
• Diarrhea, especially when starting treatment
• Low blood sugar symptoms such as sweating, shakiness or dizziness
• Metallic taste in the mouth
• Loss of appetite
• Headache
• Weight gain over time
• Signs of lactic acidosis such as unusual muscle pain, trouble breathing or severe tiredness (rare, seek urgent care)

Storage Conditions

Store below 30°C in a cool, dry place away from direct sunlight. Keep out of reach of children.