Imidol Tablet 25mg

About Imidol Tablet 25mg

Imidol Tablet Uses

• Treats major depressive disorder in adults
• Manages childhood enuresis (bedwetting) in children over 6 years
• Helps control panic disorder in some patients
• Used off label for certain chronic and neuropathic pain conditions

Imidol Tablet Benefits

• Improves mood and reduces feelings of sadness over several weeks of use
• Restores normal sleep patterns disrupted by depression
• Reduces episodes of bedwetting in children when behavioral methods fail
• Eases anxiety symptoms linked with panic attacks

What Experts Say

Imipramine belongs to the tricyclic antidepressant class. It works by blocking reuptake of serotonin and norepinephrine at the neuronal synapse, raising their brain concentration. This is believed to correct the chemical imbalance linked with depression. Full effect usually takes two to four weeks to appear, so patients should continue treatment even if early improvement feels slow.

Beyond its antidepressant action, imipramine affects the bladder muscle, which explains its use in reducing nighttime bedwetting in children. This benefit is linked to its anticholinergic properties and its effect on the sleep arousal threshold. Dosing protocols for enuresis are well established and generally involve lower doses than those used for depression.

Tricyclic antidepressants like imipramine also block histamine and alpha adrenergic receptors, which explains side effects such as drowsiness, dry mouth, and low blood pressure on standing. Clinicians start with a low dose and increase it gradually, while monitoring cardiac conduction, since the drug can affect heart rhythm in susceptible individuals.

Drug Class

• Tricyclic Antidepressant (TCA)

Imidol Tablet 25mg formula

• Imipramine Hydrochloride

Available forms

• Tablet

How to use Imidol Tablet 25mg?

• Take this tablet by mouth, usually once daily at bedtime or as directed by your doctor.
• Swallow the tablet whole with a glass of water.
• Take it at the same time every day for the best results.
• Do not stop taking this medicine suddenly without consulting your doctor.
• Take a missed dose as soon as remembered unless it is close to the next dose.

Drug Interactions

• Monoamine Oxidase Inhibitors: Combining with MAOIs can cause a dangerous rise in blood pressure and serotonin syndrome.
• Other Serotonergic Drugs: Using with SSRIs or tramadol increases the risk of serotonin syndrome.
• Anticholinergic Drugs: Combining raises the risk of severe constipation, urinary retention, and confusion.
• CNS Depressants: Alcohol and sedatives increase drowsiness and impair coordination.
• Quinidine and Antiarrhythmics: Concurrent use raises the risk of heart rhythm disturbances.

Risks and warnings

• Suicidal Thoughts: Antidepressants may increase suicidal thoughts in children, teenagers, and young adults, especially in early treatment.
• Cardiac Risk: Use with caution in patients with heart disease because imipramine can affect heart rhythm.
• Sedation: Avoid driving or operating machinery until you know how this medicine affects you.
• Withdrawal: Stopping suddenly can cause nausea, headache, and irritability, taper the dose under medical supervision.
• Elderly Use: Older adults are more sensitive to dizziness, confusion, and low blood pressure with this medicine.

Imidol Tablet Side Effects

• Drowsiness or sedation
• Dry mouth
• Blurred vision
• Constipation
• Weight gain
• Dizziness on standing up (orthostatic hypotension)
• Sweating
• Rapid heartbeat or palpitations
• Difficulty urinating
• Confusion, especially in older adults
• Seizures in rare cases with high doses
• Irregular heart rhythm in overdose or sensitive patients

Storage Conditions

• Store below 30 degrees Celsius in a cool, dry place away from direct sunlight.
• Keep the tablets in their original blister strip until ready to use.
• Keep out of reach of children and pets.
• Discard expired or unused tablets safely through a pharmacy take back program.