Inosita Plus Tablet 50mg / 1000mg

About Inosita Plus Tablet 50mg / 1000mg

Inosita Plus Uses

• Control of blood sugar in adults with type 2 diabetes.
• Add on treatment when metformin or sitagliptin alone is not enough.
• Support to diet and exercise for better HbA1c levels.

Inosita Plus Benefits

• Two medicines in one tablet reduce the pill burden.
• Lowers blood sugar through two different actions.
• Sitagliptin has a low risk of causing hypoglycemia when used with metformin alone.

What Experts Say

Inosita Plus combines sitagliptin, a DPP 4 inhibitor, with metformin, a biguanide. Sitagliptin helps the body release more insulin after meals and lowers the sugar released by the liver. Metformin reduces liver sugar output and improves how the body responds to insulin.

The combination is prescribed for adults with type 2 diabetes who need more control than lifestyle changes give. It is not used for type 1 diabetes or diabetic ketoacidosis. Doctors check kidney function before and during treatment because metformin is cleared by the kidneys.

Taking the tablet with meals reduces stomach upset. Rare but serious problems include lactic acidosis and pancreatitis, so severe stomach pain or unusual tiredness needs prompt care. Regular sugar and HbA1c checks guide the dose. Patients should keep up a balanced Pakistani diet low in refined carbohydrates and sweets, since the tablet works best alongside food and activity changes. Regular HbA1c testing every three months shows how well the treatment is working.

Drug Class

• DPP 4 inhibitor and biguanide combination

Inosita Plus Tablet 50mg / 1000mg formula

• Sitagliptin
• Metformin hydrochloride

Available forms

• Tablet

How to use Inosita Plus Tablet 50mg / 1000mg?

• Adults: one tablet twice daily with meals, or as prescribed by the doctor.
• Swallow whole with water and do not crush or chew.
• Take at the same times each day to keep blood sugar steady.
• Dose may be changed by the doctor according to kidney function and sugar levels.

Drug Interactions

• Insulin and sulfonylureas: Together they can cause low blood sugar, so the dose may need reducing.
• Alcohol: It raises the risk of lactic acidosis and low sugar.
• Contrast dyes: Iodine contrast can affect the kidneys and raise metformin related risk.
• Diuretics and steroids: They may raise blood sugar and weaken control.
• Cimetidine and similar medicines: They may increase metformin levels in the blood.
• Digoxin: Sitagliptin may slightly raise its levels, so monitoring is advised.

Risks and warnings

• Lactic acidosis: Rare but serious, and risk rises with kidney disease, heavy alcohol use and dehydration.
• Kidney problems: Not suitable in moderate to severe kidney impairment, so kidney tests are needed.
• Pancreatitis: Stop and seek care for severe, persistent stomach pain.
• Contrast dye and surgery: Metformin may need to be paused before scans with dye or surgery.
• Type 1 diabetes: It should not be used in type 1 diabetes or ketoacidosis.
• Pregnancy and breastfeeding: Use only if the doctor advises, as insulin is usually preferred.

Inosita Plus Tablet 50mg / 1000mg Side Effects

• Nausea
• Diarrhea
• Stomach pain or bloating
• Headache
• Metallic taste
• Upper respiratory infection symptoms
• Low blood sugar (with insulin or sulfonylureas)
• Joint pain (rare)

Storage Conditions

• Store below 30 C in a dry place, away from heat and humidity.
• Keep tablets in the original blister until use.
• Do not use after the expiry date on the pack.
• Keep out of reach of children.