Kare Tablet 200mg

About Kare Tablet 200mg

Kare Tablet Uses

• Fungal skin infections such as ringworm and athlete's foot
• Candidiasis affecting the skin, mouth, or other body areas
• Seborrheic dermatitis that has not responded to topical treatment
• Systemic fungal infections when other antifungal options are not suitable

Kare Tablet Benefits

• Broad antifungal action against several fungal species
• Useful for infections that resist topical antifungal creams
• Simple once daily dosing improves treatment adherence

What Experts Say

Ketoconazole works by blocking an enzyme fungi need to build their cell membrane, called 14 alpha demethylase. This action weakens the fungal cell wall and stops the organism from growing. The tablet form is generally reserved for infections that do not respond to topical antifungal creams.

Pakistani physicians usually prescribe this tablet with a meal, since stomach acid helps the body absorb the drug properly. Treatment courses generally run for two to four weeks depending on how deep the infection sits in the skin or body tissue, and doses are rarely extended beyond what is clinically necessary.

Oral ketoconazole carries a recognized risk of liver injury, so doctors in Pakistan typically order liver function tests before starting treatment and periodically during longer courses. This monitoring approach is why the tablet remains a prescription only medicine rather than an over the counter option.

Drug Class

• Imidazole Antifungal

Kare Tablet 200mg formula

• Ketoconazole 200mg

Available forms

• Tablet

How to use Kare Tablet 200mg?

• This tablet is usually taken with a meal, since food improves how well the body absorbs the medicine.
• A gap of at least two hours is kept between this tablet and any antacid or acid reducing medicine.
• The full course is completed as prescribed, even if the skin looks better after a few days.
• This tablet is swallowed whole with a full glass of water, without crushing or chewing.
• The same time each day is chosen for the dose, to keep drug levels steady in the body.

Drug Interactions

• Statins: Ketoconazole raises statin levels in the blood, increasing the risk of muscle damage.
• Antacids And PPIs: Antacids, H2 blockers, and proton pump inhibitors reduce how well this tablet is absorbed.
• Warfarin: This medicine can increase the blood thinning effect of warfarin, raising bleeding risk.
• Rifampicin: Rifampicin lowers ketoconazole levels in the blood, reducing its antifungal effect.
• Corticosteroids: This medicine can raise corticosteroid levels in the body, needing careful dose review.

Risks and warnings

• Liver Toxicity: Ketoconazole tablets carry a recognized risk of serious liver injury, so liver function is checked before and during treatment.
• Alcohol Use: Alcohol is avoided during treatment, since it adds to the strain on the liver.
• Adrenal Function: High doses can reduce the body's natural steroid hormone production, so long courses are monitored closely.
• Heart Rhythm: This medicine can affect heart rhythm when combined with certain other drugs, so a full medicine list is shared with the doctor.
• Pregnancy: This tablet is generally avoided during pregnancy unless clearly needed and prescribed by a doctor.

Kare Tablet Side Effects

• Nausea
• Vomiting
• Stomach pain
• Headache
• Dizziness
• Skin rash or itching
• Rare serious liver injury, including jaundice
• Rare reduced adrenal hormone production
• Rare breast enlargement in men with prolonged use

Storage Conditions

• Store below 30°C in a cool, dry place away from direct sunlight.
• Keep the tablets in their original blister pack until ready to use.
• Protect from moisture and humidity, especially in a bathroom cabinet.
• Keep out of reach of children at all times.