About Keflex Capsule 250mg
Keflex Capsule 250mg (Cephalexin) is a first generation cephalosporin antibiotic for bacterial infections.
Keflex Capsule 250mg Uses
- Respiratory tract infections, including bronchitis and pharyngitis
- Skin and soft tissue infections such as cellulitis and impetigo
- Urinary tract infections
- Ear infections (otitis media)
- Bone infections (osteomyelitis)
- Prevention of infection before certain dental or minor surgical procedures
Keflex Capsule 250mg Benefits
- Clears susceptible bacterial infections effectively when taken as prescribed
- Offers a convenient oral option for infections that would otherwise need injectable therapy
- Fast acting, with symptom relief often noticed within a few days
- Well tolerated by most adults and older children
- Affordable compared to newer generation antibiotics for similar indications
What Experts Say
Cephalexin is a first generation cephalosporin antibiotic. It works by binding to penicillin binding proteins on the bacterial cell wall, blocking the final step of cell wall synthesis. This action is bactericidal, so it kills susceptible bacteria rather than only slowing their growth.
The drug is active against many gram positive organisms, including Streptococcus and methicillin sensitive Staphylococcus aureus, along with some gram negative bacteria such as E. coli and Klebsiella. It does not cover methicillin resistant Staphylococcus aureus or Pseudomonas, so sensitivity testing guides therapy in resistant infections.
Cephalexin is well absorbed orally and reaches peak blood levels within about an hour. It is cleared largely unchanged through the kidneys, so consistent dosing intervals matter. Completing the full course, even after symptoms improve, helps clear the infection fully and limits antibiotic resistance.
Drug Class
- Cephalosporin antibiotic (first generation)
Keflex Capsule 250mg Uses in Urdu
- سانس کی نالی کے انفیکشن جیسے برونکائٹس اور گلے کی سوزش
- جلد اور نرم بافتوں کے انفیکشن
- پیشاب کی نالی کے انفیکشن
- کان کا انفیکشن
- ہڈیوں کا انفیکشن
- بعض دانتوں یا معمولی سرجریوں سے پہلے انفیکشن سے بچاؤ کے لیے
Keflex Capsule 250mg formula
How to use Keflex Capsule 250mg?
- Take Keflex Capsule 250mg by mouth with or without food, as advised by the doctor.
- Swallow the capsule whole with a full glass of water.
- Take doses at evenly spaced intervals, usually every 6 hours, to keep a steady level in the body.
- Complete the full course even if symptoms improve early, since stopping early can lead to antibiotic resistance.
- Do not double the dose to make up for a missed one, take it as soon as remembered unless the next dose is near.
Drug Interactions
- Metformin: Cephalexin can raise metformin blood levels, so blood sugar should be monitored closely.
- Probenecid: This gout medicine slows the elimination of Cephalexin, which can raise its blood levels and side effect risk.
- Warfarin: Cephalexin may enhance the blood thinning effect, so clotting levels should be checked more often.
- Live Bacterial Vaccines: Antibiotics like Cephalexin can reduce the effectiveness of live vaccines such as the typhoid vaccine.
- Other Antibiotics: Combining Cephalexin with other antibiotics should only be done under medical supervision to avoid reduced effectiveness or added side effects.
Risks and warnings
- Penicillin Allergy: People with a history of severe penicillin allergy should use Keflex Capsule 250mg with caution, since cross reactivity with cephalosporins can occur.
- Kidney Impairment: Patients with reduced kidney function need a lower dose, since Cephalexin is cleared through the kidneys.
- Clostridioides Difficile Diarrhea: Prolonged or repeated antibiotic use can trigger severe diarrhea caused by bacterial overgrowth, even weeks after stopping the medicine.
- Pregnancy And Breastfeeding: Keflex Capsule 250mg is generally considered safe in pregnancy and breastfeeding, but a doctor should confirm the correct dose first.
- Seizure Disorder: People with a history of seizures should be monitored closely, since high doses of Cephalexin have rarely been linked to convulsions.
Keflex Capsule 250mg Side Effects
- Nausea
- Diarrhea
- Stomach upset or pain
- Vomiting
- Headache
- Dizziness
- Vaginal itching or discharge
- Skin rash or hives
- Severe allergic reaction with swelling of the face, lips, or throat
- Severe watery or bloody diarrhea, a possible sign of Clostridioides difficile infection
- Unusual bruising or bleeding
- Yellowing of the skin or eyes, a sign of liver problems
Storage Conditions
- Store at room temperature, between 15 and 30 degrees Celsius.
- Keep the capsules in their original blister pack away from moisture.
- Protect from direct sunlight and heat.
- Keep out of reach of children.
- Discard any unused or expired capsules safely.