Lice-O-Nil Cream 1%

About Lice-O-Nil Cream 1%

Lice-O-Nil Cream 1% Uses

• Treatment of head lice (pediculosis capitis) infestation
• Treatment of body lice (pediculosis corporis) infestation
• Treatment of pubic lice (pediculosis pubis) infestation
• Treatment of scabies caused by Sarcoptes scabiei mites

Lice-O-Nil Cream 1% Benefits

• Kills adult lice and scabies mites on contact
• Single correctly timed application often clears mild infestations
• Affordable option available at most Pakistani pharmacies
• Reduces itching and skin irritation caused by mite burrows

What Experts Say

Lindane works by being absorbed through the outer covering of lice and scabies mites. Once inside the parasite, it disrupts GABA gated chloride channels in the nervous system, causing uncontrolled nerve firing, paralysis, and death of the organism within hours of contact. This mechanism explains why a single correctly timed application can clear most infestations.

Because Lindane also crosses human skin and, to a smaller degree, the blood brain barrier, dermatologists reserve it as a second line option after permethrin or benzyl benzoate fail. Prolonged contact, broken skin, or use in infants and young children raises the chance of neurotoxic effects including seizures, which is why many prescribers now limit its role to resistant cases.

Correct technique matters more than repeat dosing. Guidelines call for one thin application left on for the exact time stated on the label, followed by thorough rinsing, since extending contact time beyond instructions increases systemic absorption without improving how well the parasites are killed.

Drug Class

• Organochlorine pediculicide and scabicide

Lice-O-Nil Cream 1% formula

• Lindane (Gamma Benzene Hexachloride) 1% w/w

Available forms

• Cream

How to use Lice-O-Nil Cream 1%?

• Wash and dry the affected area before application
• Apply a thin layer of Lice-O-Nil Cream to the scalp, hair, or affected skin as directed by the pharmacist or doctor
• Leave the cream on for the exact time mentioned on the pack insert, do not exceed it
• Rinse off thoroughly with water once the contact time is complete
• Repeat treatment only if live lice or mites are seen after seven to ten days, and only on medical advice

Drug Interactions

• Oily Lotions Or Mineral Oil: Applying oil based products on the same skin area increases Lindane absorption and toxicity risk
• CNS Depressants Or Anticonvulsant Therapy: Concurrent use needs caution since Lindane toxicity can lower the seizure threshold

Risks and warnings

• Neurotoxicity Risk: Lindane can cause seizures if absorbed in excess, so it should never be left on the skin longer than instructed
• Not For Infants: Avoid use in premature infants and young children due to higher absorption through thin skin
• Broken Skin: Do not apply on open wounds, raw or infected skin since absorption increases significantly
• Pregnancy And Breastfeeding: Use only under medical supervision since Lindane can pass into breast milk
• Second Line Treatment: Doctors generally recommend permethrin based products first, reserving Lindane for cases that do not respond

Lice-O-Nil Cream 1% Side Effects

• Skin redness and irritation at the application site
• Itching or burning sensation
• Dryness of the scalp or skin
• Dizziness or headache with excess absorption
• Numbness or tingling of the skin
• Seizures in rare cases of overuse or accidental ingestion

Storage Conditions

• Store below 30°C in a cool, dry place away from direct sunlight
• Keep the tube tightly closed after each use
• Keep out of reach of children
• Do not store in the bathroom where humidity is high