Lowplat Plus Tablet 75mg / 150mg

About Lowplat Plus Tablet 75mg / 150mg

Uses

• Prevention of heart attack in patients with acute coronary syndrome
• Prevention of stroke in patients at high risk of blood clots
• Reduced risk of clot formation after coronary stent placement
• Long term cardiovascular protection in peripheral artery disease
• Secondary prevention after a previous heart attack or stroke

Benefits

• Combines two antiplatelet mechanisms for stronger clot prevention
• Lower chance of stent blockage after angioplasty
• Reduced overall risk of major cardiovascular events
• Single tablet convenience instead of two separate pills
• Well established combination with a long safety record

What Experts Say

Cardiologists prescribe Lowplat Plus because clopidogrel and aspirin act through different pathways to stop platelets from clumping. Aspirin blocks thromboxane production while clopidogrel blocks the P2Y12 receptor. This dual action gives stronger clot protection than either drug alone, which is why the combination is standard after a heart attack or stent placement.

Doctors usually prescribe this dual therapy for a set period, often around twelve months after a stent or acute coronary event, before reassessing whether the patient can continue on a single antiplatelet drug. This limit matters because combining two antiplatelet agents raises bleeding risk compared with using just one. Physicians weigh clotting risk against bleeding risk before deciding treatment length.

Pakistan carries a heavy burden of heart disease, with many patients presenting at a comparatively young age due to high rates of diabetes, hypertension and smoking. Physicians rely on affordable generic combinations like Lowplat Plus to keep dual antiplatelet therapy accessible after cardiac events. Regular follow up lets doctors watch for bruising, bleeding or stomach upset during treatment.

Drug Class

• Antiplatelet agent
• P2Y12 receptor inhibitor (Clopidogrel)
• Cyclooxygenase inhibitor (Aspirin)
• Dual antiplatelet therapy combination

Lowplat Plus Tablet 75mg / 150mg formula

• Clopidogrel 75mg + Aspirin 150mg

Available forms

• Tablet

How to use Lowplat Plus Tablet 75mg / 150mg?

• Take one tablet daily as prescribed by your doctor, usually after a meal.
• Swallow the tablet whole with a glass of water, do not crush or chew it.
• Take the medicine at the same time every day to keep blood levels steady.
• Do not double the dose if a dose is missed, just take the next dose on schedule.
• Continue taking this medicine for as long as your doctor recommends, even if you feel well.
• Do not stop this medicine suddenly without consulting your doctor, especially if you have a heart stent.

Drug Interactions

• Warfarin and Other Anticoagulants: Combined use significantly increases the risk of serious bleeding.
• NSAIDs (Ibuprofen, Diclofenac): Raises the risk of stomach irritation and gastrointestinal bleeding.
• Proton Pump Inhibitors (Omeprazole): Some PPIs may reduce clopidogrel's effectiveness when taken together.
• SSRIs (Fluoxetine, Sertraline): These antidepressants can add to the bleeding risk of this medicine.
• Heparin: Using heparin alongside this medicine raises the combined risk of bleeding.

Risks and warnings

• Bleeding Risk: This combination increases the risk of bleeding and bruising more than either drug alone, including nosebleeds and bleeding gums.
• Before Surgery: Do not stop this medicine abruptly before any surgery or dental procedure without your doctor's advice, since sudden stopping can raise the risk of stent blockage or heart attack.
• GI Bleeding: Long term use can irritate the stomach lining and lead to ulcers or gastrointestinal bleeding, especially in patients with a history of ulcers.
• Other Blood Thinners: Combining this medicine with other anticoagulants or antiplatelet drugs such as warfarin or heparin needs caution, since the bleeding risk becomes significantly higher.
• Allergy: Avoid this medicine if you have a known allergy to aspirin, clopidogrel, or other NSAIDs.
• Kidney or Liver Disease: Use with caution in patients with significant kidney or liver impairment, dose adjustment may be needed.
• Pregnancy and Breastfeeding: Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding, since safety needs individual assessment.

Lowplat Plus Tablet 75mg / 150mg Side Effects

• Easy bruising
• Bleeding gums or nosebleeds
• Upset stomach or indigestion
• Diarrhea or constipation
• Headache
• Dizziness
• Skin rash or itching
• Prolonged bleeding from small cuts

Storage Conditions

• Store at room temperature, below 30°C.
• Keep away from direct sunlight and moisture.
• Keep the tablets in their original blister pack until ready to use.
• Keep out of reach of children.
• Do not use after the expiry date printed on the pack.