M-Low Tablet 5 mg

About M-Low Tablet 5 mg

M-Low Tablet 5 mg Uses

• Treating mild to moderate high blood pressure (hypertension)
• Preventing episodes of chest pain (angina)
• Used as the standard starting dose for adults new to blood pressure treatment
• Managing coronary artery disease
• Lowering the long-term risk of stroke and heart attack linked to high blood pressure
• Sometimes prescribed off-label for Raynaud's phenomenon

M-Low Tablet 5 mg Benefits

• Once-daily dosing makes it easy to fit into a daily routine
• Long half-life gives steady 24-hour blood pressure control
• Lower starting strength reduces the chance of ankle swelling and dizziness
• Well suited for elderly patients or those sensitive to stronger doses
• Can be combined with other blood pressure medicines later if needed

What Experts Say

Amlodipine belongs to the dihydropyridine class of calcium channel blockers. It works by relaxing the smooth muscle in blood vessel walls, which widens the arteries and lowers the resistance the heart must pump against. This action lowers blood pressure gradually over several hours rather than causing a sudden drop.

Physicians typically start adult patients on the 5mg dose rather than jumping straight to 10mg, since the lower strength carries a smaller risk of ankle swelling, flushing and dizziness while still giving meaningful blood pressure control within one to two weeks. Dose is usually reviewed after two to four weeks and only raised if control remains inadequate.

Pakistan carries a high burden of hypertension and related cardiovascular disease, so doctors recommend that patients on this dose keep regular blood pressure checks and report new swelling or palpitations promptly. Elderly patients and those with liver impairment are usually kept on this lower starting dose for longer before any increase is considered.

Drug Class

• Calcium Channel Blocker
• Dihydropyridine

M-Low Tablet 5 mg formula

• Amlodipine 5mg

Available forms

• Tablet

How to use M-Low Tablet 5 mg?

• Take one tablet by mouth once daily, with or without food.
• Swallow the tablet whole with a glass of water; do not crush or chew it.
• Take it at the same time every day to keep blood levels steady.
• Do not stop taking it suddenly without talking to your doctor.
• If you miss a dose, take it as soon as you remember unless it is close to the next dose.
• Your doctor may raise the dose to 10mg if blood pressure stays high after a few weeks.
• Keep taking it even if you feel well, since high blood pressure often has no symptoms.

Drug Interactions

• Simvastatin: Amlodipine can raise simvastatin levels, increasing the risk of muscle-related side effects.
• Other Antihypertensives: Combining with beta blockers or ACE inhibitors can cause additive blood pressure lowering.
• CYP3A4 Inhibitors: Drugs like ketoconazole or clarithromycin can raise amlodipine blood levels.
• NSAIDs: Regular use of painkillers such as diclofenac may reduce its blood pressure lowering effect.
• Cyclosporine: Amlodipine may increase cyclosporine levels, requiring dose adjustment.

Risks and warnings

• Ankle Swelling: Amlodipine can cause fluid buildup in the ankles and feet, more common at higher doses.
• Low Blood Pressure: Combining it with other blood pressure medicines can cause dizziness or fainting.
• Liver Impairment: Patients with liver disease may need a lower dose and closer monitoring.
• Pregnancy: Use only if clearly needed and under medical supervision, since safety data in pregnancy is limited.
• Heart Failure: Should be used cautiously in patients with severe heart failure.
• Grapefruit Juice: Large amounts can raise drug levels in the blood and increase side effect risk.
• Elderly Patients: May be more sensitive to its blood pressure lowering effect and need slower dose changes.

M-Low Tablet 5 mg Side Effects

• Swelling of the ankles or feet
• Flushing or warmth in the face
• Headache
• Dizziness or lightheadedness
• Fatigue or tiredness
• Palpitations or a fast heartbeat
• Nausea
• Abdominal pain
• Muscle cramps
• Drowsiness
• Skin rash
• Gum swelling with long-term use

Storage Conditions

• Store below 30°C in a cool, dry place.
• Keep the tablets in their original blister pack until ready to use.
• Protect from direct sunlight and moisture.
• Keep out of reach of children.