Maradol Injection 50mg/ml

About Maradol Injection 50mg/ml

Maradol Injection 50mg/ml Uses

• Manages moderate to severe pain after surgery
• Controls pain from trauma, fractures and burns
• Used for cancer related pain in hospital care
• Helpful when oral pain relief is not practical

Maradol Injection 50mg/ml Benefits

• Fast acting when given through IV or IM route
• Effective for pain that does not respond to milder analgesics
• Lower risk of severe respiratory depression than strong opioids at normal doses
• Flexible dosing for inpatient pain control

What Experts Say

Tramadol works through two pathways. It binds weakly to opioid receptors and also blocks the reuptake of serotonin and norepinephrine, which adds an extra layer of pain control beyond typical opioids.

Doctors use the injectable form mainly in hospitals and emergency rooms for patients who need quick, reliable pain relief after surgery or major injury. Because it is an opioid, it carries a real risk of dependence, sedation and interaction with other central nervous system depressants.

In Pakistan, tramadol injections are tightly controlled and given under direct medical supervision. Doctors monitor breathing rate and consciousness closely, especially in elderly patients or those with kidney or liver problems.

Drug Class

• Opioid analgesics
• Centrally acting pain relievers
• Controlled substances

Maradol Injection 50mg/ml formula

• Tramadol Hydrochloride 50mg/ml

Available forms

• Injection

How to use Maradol Injection 50mg/ml?

• To be administered only by a doctor or trained healthcare professional
• Given by slow intravenous or intramuscular injection
• Dose is adjusted based on pain severity and patient response
• Not for self administration at home
• Patients are monitored for breathing and alertness after injection

Drug Interactions

• SSRIs and SNRIs: Combining with these antidepressants raises the risk of serotonin syndrome.
• MAOIs: Should not be used together, as the combination can cause a severe reaction.
• Benzodiazepines and CNS depressants: Increase the risk of severe sedation and slowed breathing.
• Carbamazepine: Can reduce tramadol's pain relieving effect by speeding up its breakdown.

Risks and warnings

• Respiratory depression: High doses can slow or stop breathing, especially in elderly or frail patients.
• Seizure risk: Tramadol can lower the seizure threshold, particularly at high doses.
• Dependence: Prolonged use can lead to tolerance and physical dependence.
• Serotonin syndrome: Combining with other serotonin affecting drugs can cause a dangerous reaction.
• Not for opioid naive elderly: Requires cautious, lower dosing in older or medically frail patients.

Maradol Injection 50mg/ml Side Effects

• Nausea
• Vomiting
• Dizziness
• Drowsiness
• Constipation
• Dry mouth
• Sweating
• Headache

Storage Conditions

• Store below 25°C, away from direct sunlight
• Keep ampoules in their original box until use
• Do not freeze the injection
• Keep in a locked area, out of reach of children and unauthorized persons