Mayoflex Tablet 500mg

About Mayoflex Tablet 500mg

Mayoflex Tablet 500mg Uses

• Relieves pain from osteoarthritis and rheumatoid arthritis
• Eases pain and swelling from ankylosing spondylitis
• Reduces menstrual cramps and lower back pain
• Manages pain from muscle sprains and strains
• Lowers fever and reduces mild to moderate pain from headaches and toothache

Drug Class

• Nonsteroidal anti-inflammatory drug (NSAID)
• Propionic acid derivative

What Experts Say

Naproxen belongs to the propionic acid class of NSAIDs and works by blocking cyclooxygenase (COX) enzymes that produce prostaglandins. This reduces the pain, swelling and stiffness linked with joint and muscle conditions. Physicians often favor naproxen because its longer half-life allows twice-daily dosing.

Pakistan carries a substantial burden of osteoarthritis and lower back pain, conditions where physical labor, limited physiotherapy access and an aging population all play a role. Naproxen 500mg is commonly used as a first-line option for moderate joint pain because it balances effective relief with a lower cardiovascular risk than some other NSAIDs, based on comparative studies.

Experts caution that NSAIDs including naproxen should be used at the lowest effective dose for the shortest duration needed, since prolonged use raises the risk of stomach ulcers, kidney strain and elevated blood pressure. Patients with heart disease, kidney impairment or peptic ulcers should discuss safer alternatives with their doctor first.

Mayoflex Tablet 500mg formula

• Naproxen 500mg

Available forms

• Tablet

How to use Mayoflex Tablet 500mg?

• Take Mayoflex Tablet 500mg by mouth, with food or milk to reduce stomach upset
• Swallow the tablet whole with a full glass of water
• The usual adult dose is 250mg to 500mg twice daily, not exceeding 1000mg in 24 hours unless directed by a doctor
• Do not use for more than 10 days for pain or 3 days for fever without medical advice
• Take at the same times each day for consistent relief

Drug Interactions

• Aspirin and other NSAIDs: increased risk of stomach bleeding
• Blood thinners such as warfarin: higher bleeding risk
• ACE inhibitors and diuretics: reduced blood pressure control and kidney strain
• Lithium: naproxen can raise lithium levels in the blood
• Methotrexate: naproxen can increase methotrexate toxicity
• Corticosteroids: combined use raises the risk of gastrointestinal ulcers

Risks and warnings

• Avoid if you have a history of stomach ulcers or gastrointestinal bleeding
• Use with caution in heart disease, high blood pressure or kidney impairment
• Not recommended during the third trimester of pregnancy
• Avoid alcohol, which increases the risk of stomach bleeding
• Long term use can raise the risk of heart attack or stroke
• Contraindicated in patients with a known naproxen or NSAID allergy, including aspirin induced asthma

Mayoflex Tablet 500mg Side Effects

• Stomach upset, heartburn or nausea
• Headache or dizziness
• Drowsiness
• Fluid retention or mild swelling in the ankles
• Ringing in the ears with high doses
• Rarely, stomach ulcers or gastrointestinal bleeding
• Rarely, allergic reactions such as rash or difficulty breathing

Storage Conditions

Store below 30°C in a cool, dry place away from direct sunlight. Keep the tablets in their original blister pack, out of reach of children.