Mephage Tablet 500mg

About Mephage Tablet 500mg

Mephage Tablet Uses

• Type 2 diabetes mellitus in adults, alongside diet and exercise
• Prediabetes management when advised by a doctor
• Polycystic ovary syndrome (PCOS) related insulin resistance, as an off label use
• Combination therapy with other antidiabetic medicines

Mephage Tablet Benefits

• Lowers fasting and post meal blood sugar levels
• Improves the body's response to its own insulin
• Weight neutral, and may support modest weight loss over time
• Low risk of hypoglycemia when used alone

What Experts Say

Metformin remains the preferred first choice medicine for type 2 diabetes because it lowers blood sugar without commonly causing weight gain or dangerously low blood sugar episodes. It works mainly by reducing glucose production in the liver and improving how muscle cells respond to insulin, rather than forcing the pancreas to release more insulin.

Clinical guidelines continue to recommend metformin as initial therapy for most adults with type 2 diabetes, usually started alongside diet changes and regular physical activity. Many patients see a meaningful drop in fasting blood sugar and HbA1c within a few weeks, though the fuller benefit on long term glucose control often takes a few months of steady use.

Doctors generally consider metformin safe for long term use, but kidney function is checked periodically since the kidneys clear the drug from the body. Stomach upset, nausea or loose stools are common when starting treatment and usually settle once the body adjusts, especially when the tablet is taken with meals instead of on an empty stomach.

Drug Class

• Biguanide
• Antidiabetic (antihyperglycemic) agent

Mephage Tablet 500mg formula

• Metformin

Available forms

• Tablet

How to use Mephage Tablet 500mg?

• Take Mephage tablet with a meal to reduce stomach upset
• Swallow the tablet whole with a glass of water
• Follow the dose and schedule set by your doctor
• If a dose is missed, take it as soon as remembered unless the next dose is due
• Continue prescribed diet and exercise changes alongside this medicine

Drug Interactions

• Iodinated Contrast Dye: Raises the risk of kidney injury and lactic acidosis
• Alcohol: Increases the risk of lactic acidosis and low blood sugar
• Diuretics: Can affect kidney function
• Corticosteroids: May raise blood sugar and reduce metformin's effect
• Cimetidine: Can raise metformin levels in the blood

Risks and warnings

• Lactic Acidosis: Rare but serious risk that is higher with kidney or liver impairment, heavy alcohol use or dehydration
• Kidney Function: Requires adequate kidney function; dose adjustment or avoidance is needed when kidney function is reduced
• Contrast Dye Procedures: Should be paused before and after imaging tests that use iodinated contrast dye
• Alcohol Use: Increases the risk of lactic acidosis and low blood sugar
• Vitamin B12 Levels: Long term use can lower vitamin B12

Mephage Tablet Side Effects

• Nausea
• Diarrhea
• Stomach upset or bloating
• Metallic taste in the mouth
• Reduced appetite
• Headache
• Vitamin B12 deficiency with long term use

Storage Conditions

• Store below 30°C in a cool, dry place
• Keep away from direct sunlight and moisture
• Keep out of reach of children
• Do not use after the expiry date printed on the pack