Metoclon IV/IM Injection 10mg

About Metoclon IV/IM Injection 10mg

Metoclon IV/IM Injection 10mg Uses

• Postoperative nausea and vomiting
• Chemotherapy induced nausea and vomiting
• Diabetic gastroparesis (delayed stomach emptying)
• Nausea and vomiting linked with migraine attacks
• Radiotherapy induced nausea
• Aiding intubation of the small bowel during diagnostic procedures
• Nausea related to reflux disease (GERD)

Metoclon IV/IM Injection 10mg Benefits

• Provides fast relief from severe nausea and vomiting
• Speeds up stomach emptying, easing bloating and discomfort
• Helps patients tolerate chemotherapy sessions more comfortably
• Reduces the risk of dehydration caused by persistent vomiting
• Acts quickly when given by IV or IM route in a hospital setting

What Experts Say

Doctors in Pakistan often prescribe metoclopramide injection when a patient cannot keep oral medicines down due to severe vomiting. It works fast by blocking dopamine receptors in the brain's vomiting center, so it acts quicker than tablets and suits emergency and hospital care. Its dual action, an antiemetic effect plus stimulation of stomach motility, also helps with delayed gastric emptying.

Gastroenterologists advise using metoclopramide at the lowest effective dose for the shortest time, generally not more than five days. Prolonged use raises the risk of movement disorders such as tardive dyskinesia. The injection should only be given under professional supervision, since it can cause drowsiness or restlessness right after the dose.

Oncologists often combine this injection with other antiemetics during chemotherapy, since metoclopramide alone may not fully control severe drug induced nausea. Patients with kidney or liver problems need dose adjustments, and this medicine should be avoided in those with a history of seizures or Parkinson's disease unless a specialist advises otherwise.

Drug Class

• Antiemetics
• Dopamine antagonists (D2 receptor blockers)
• Prokinetic agents

Metoclon IV/IM Injection 10mg formula

• Metoclopramide 10mg

Available forms

• Box of 20 Ampoules (2mL each)

How to use Metoclon IV/IM Injection 10mg?

• Metoclon IV/IM Injection 10mg is given only by a doctor or trained healthcare professional in a hospital or clinic.
• The injection may be administered slowly into a vein (IV) or into a muscle (IM), depending on the clinical situation.
• The usual adult dose is 10mg given up to three times a day, not exceeding 30mg or 0.5mg per kg of body weight in 24 hours.
• Treatment is generally limited to five days to lower the risk of side effects.
• Dosing in children and elderly patients is adjusted by the treating physician based on body weight and condition.
• Patients should never attempt to self-administer this injection at home.

Drug Interactions

• Antipsychotics: Combining this injection with antipsychotic medicines increases the risk of extrapyramidal symptoms and movement disorders.
• Sedatives and Alcohol: Using this injection with sedatives, sleeping pills, or alcohol can increase drowsiness and slow reaction time.
• Anticholinergic Drugs: Medicines such as atropine can reduce the stomach emptying effect of this injection.
• SSRIs (Antidepressants): Combined use may raise the risk of serotonin related side effects and movement disorders.
• Digoxin: This injection may reduce the absorption of digoxin, so blood levels may need monitoring.
• MAO Inhibitors: Concurrent use may raise blood pressure and increase the risk of side effects.

Risks and warnings

• Extrapyramidal Symptoms: This injection can cause involuntary muscle movements, especially in children, young adults, and at higher doses.
• Tardive Dyskinesia: Prolonged or repeated use may lead to irreversible involuntary movements of the face and body, so treatment beyond five days is not recommended.
• Parkinson's Disease: This medicine can worsen Parkinsonian symptoms and should be used with caution in patients with this condition.
• Seizure Disorders: Metoclopramide may lower the seizure threshold, so it should be avoided or used carefully in people with epilepsy.
• Gastrointestinal Obstruction: This injection should not be used in patients with bowel obstruction, perforation, or active gastrointestinal bleeding.
• Kidney or Liver Impairment: Patients with reduced kidney or liver function may need a lower dose under close medical supervision.
• Pregnancy and Breastfeeding: This injection should only be used during pregnancy or breastfeeding if a doctor considers it clearly necessary.

Metoclon IV/IM Injection 10mg Side Effects

• Drowsiness or fatigue
• Restlessness or feeling anxious
• Headache
• Dizziness
• Diarrhea
• Dry mouth
• Low blood pressure after the injection
• Involuntary muscle spasms or movement disorders
• Irregular heartbeat (rare)
• Allergic reactions such as rash or swelling (rare)

Storage Conditions

• Store below 25°C, away from direct sunlight.
• Keep the ampoules in their original box until ready for use.
• Do not freeze.
• Keep out of reach of children.
• Discard any unused portion after opening an ampoule.