Myrin Tablet 300mg / 75mg / 150mg

About Myrin Tablet 300mg / 75mg / 150mg

Myrin Tablet 300mg / 75mg / 150mg Uses

• Treats active pulmonary tuberculosis as part of a combination anti TB regimen prescribed by a physician
• Treats extrapulmonary tuberculosis affecting lymph nodes, bones or other organs under specialist supervision
• Used in the continuation phase of TB treatment after the initial intensive phase, as directed by a TB program or physician
• Supports completion of the full TB treatment course, which helps prevent drug resistant tuberculosis

Myrin Tablet 300mg / 75mg / 150mg Benefits

• Combines three anti TB medicines in one tablet, making the daily dosing schedule simpler for patients
• Simplified dosing supports better adherence to the long TB treatment course
• Each ingredient targets the tuberculosis bacteria through a different mechanism, reducing the chance of resistance
• Fixed dose combination reduces the number of tablets a patient needs to take each day

What Experts Say

Tuberculosis is treated with more than one medicine at the same time because a single drug allows resistant bacteria to survive and multiply. Combining rifampicin, isoniazid and ethambutol in one tablet attacks the bacteria through different pathways at once, which is why doctors rarely treat active TB with just one medicine alone.

Doctors monitor liver function closely during treatment because rifampicin and isoniazid can both affect the liver, especially when taken together. Vision checks are also recommended periodically since ethambutol, in rare cases, can affect the optic nerve. Any change in eyesight or unusual yellowing of the skin should be reported right away.

Completing the full prescribed course matters more than most patients realize, since stopping early is one of the main causes of drug resistant tuberculosis. Physicians typically prescribe vitamin B6 alongside this combination to reduce nerve related side effects from isoniazid. Missing doses or self adjusting the schedule should always be avoided.

Drug Class

• Fixed dose combination antituberculosis antibiotic (Rifampicin, Isoniazid and Ethambutol)

Myrin Tablet 300mg / 75mg / 150mg formula

• Ethambutol + Isoniazid + Rifampicin

Available forms

• Tablet

How to use Myrin Tablet 300mg / 75mg / 150mg?

• Take Myrin exactly as prescribed by your physician or TB treatment program, usually once daily
• Take on an empty stomach, at least one hour before or two hours after a meal, for best absorption
• Swallow the tablet with a full glass of water
• Take the medicine at the same time every day to keep drug levels steady in the body
• Complete the entire prescribed course even after symptoms improve
• Take vitamin B6 supplements if advised by your doctor to reduce nerve related side effects
• Do not skip doses, since irregular use increases the risk of drug resistant tuberculosis

Drug Interactions

• Oral Contraceptives: Rifampicin reduces the effectiveness of hormonal birth control, so an alternative contraceptive method is recommended during treatment
• Warfarin: Rifampicin lowers warfarin blood levels, often requiring a higher anticoagulant dose with closer monitoring
• Phenytoin: Isoniazid can raise phenytoin levels, increasing the risk of side effects from the seizure medicine
• Antacids: Aluminum containing antacids reduce absorption of ethambutol and isoniazid, so doses should be separated by a few hours
• Alcohol: Increases the risk of liver toxicity when combined with rifampicin and isoniazid
• Antiretroviral Medicines: Rifampicin interacts with many HIV medicines, requiring dose adjustment under specialist supervision
• Corticosteroids: Rifampicin can reduce the effectiveness of steroid medicines by speeding up their breakdown in the liver

Risks and warnings

• Liver Toxicity: Rifampicin and isoniazid can both affect the liver, so liver function tests are checked before and during treatment
• Vision Changes: Ethambutol can rarely affect the optic nerve, causing blurred vision or difficulty telling red and green apart, so eye checks are recommended for longer courses
• Peripheral Neuropathy: Isoniazid can cause tingling or numbness in the hands and feet, which vitamin B6 supplementation helps prevent
• Body Fluid Discoloration: Rifampicin turns urine, sweat, saliva and tears reddish orange, which is harmless but can stain soft contact lenses
• Reduced Effectiveness Of Other Medicines: Rifampicin speeds up liver breakdown of many drugs, including hormonal contraceptives, so backup contraception is advised
• Pregnancy And Breastfeeding: Use only under medical supervision, since dosing and monitoring needs differ during pregnancy
• Alcohol Use: Increases the risk of liver damage when combined with this medicine

Myrin Tablet 300mg / 75mg / 150mg Side Effects

• Nausea and vomiting
• Loss of appetite
• Stomach pain
• Reddish orange discoloration of urine, sweat and tears
• Skin rash or itching
• Headache
• Tingling or numbness in hands and feet
• Joint pain
• Blurred vision or changes in color perception
• Yellowing of skin or eyes as a sign of liver involvement
• Unusual tiredness
• Flu like symptoms including fever and chills

Storage Conditions

• Store below 30 degrees Celsius in a cool, dry place away from direct sunlight
• Keep the tablets in their original blister strip until the dose is due
• Keep out of reach of children
• Avoid storing in humid areas such as the bathroom
• Dispose of expired or leftover tablets safely rather than keeping them beyond the treatment course