Natrilam MR 5/1.5 Tablet

About Natrilam MR 5/1.5 Tablet

Natrilam MR 5/1.5 Tablet Uses

• High blood pressure not fully controlled on a single medicine.
• Long term blood pressure management in adults.
• Reduced heart workload from persistent hypertension.
• Long term risk reduction for stroke and heart complications linked to uncontrolled blood pressure.

Natrilam MR 5/1.5 Tablet Benefits

• Two blood pressure lowering mechanisms work together in a single tablet.
• Modified release formulation supports smoother blood pressure control through the day.
• Once daily dosing improves convenience and treatment adherence.
• One tablet often replaces the need for two separate medicines.

What Experts Say

Amlodipine relaxes and widens blood vessels by blocking calcium from entering the muscle cells in vessel walls, while indapamide, a thiazide like diuretic, helps the kidneys remove excess salt and water from the body. Together these two actions lower blood pressure through different pathways at the same time.

Physicians often move patients to a combination tablet like this one when blood pressure remains high despite a single medicine at an adequate dose, since combining lower doses of two drugs can control pressure with fewer side effects than pushing one drug higher. Regular monitoring of blood pressure, kidney function and electrolyte levels is advised during treatment.

Uncontrolled high blood pressure is common in this region partly because many patients stop treatment once symptoms disappear, not realizing that blood pressure can stay dangerously high without any obvious warning signs. A combination tablet that needs to be taken only once a day can make it easier for busy patients to stay consistent with treatment.

Drug Class

• Calcium Channel Blocker and Thiazide Like Diuretic Combination

Natrilam MR 5/1.5 Tablet formula

• Amlodipine
• Indapamide

Available forms

• Tablet

How to use Natrilam MR 5/1.5 Tablet?

• Take one tablet once daily, preferably at the same time each day.
• Swallow the tablet whole without crushing or chewing, since it is a modified release formulation.
• Take with or without food, as advised by your doctor.
• Do not stop the tablet suddenly without medical advice.
• Attend regular checkups to monitor blood pressure and kidney function.

Drug Interactions

• Lithium: The diuretic component can raise lithium blood levels, increasing toxicity risk.
• Other Blood Pressure Medicines: Combined use can add to the blood pressure lowering effect, requiring dose caution.
• NSAIDs: Regular use can reduce the effectiveness of this combination and affect kidney function.
• Digoxin: Low potassium from the diuretic component can increase the risk of digoxin related heart rhythm problems.

Risks and warnings

• Low Blood Pressure: Dizziness or fainting can occur, especially when standing up quickly or starting treatment.
• Electrolyte Imbalance: The diuretic component can lower sodium or potassium levels, requiring periodic blood tests.
• Pregnancy Risk: This combination should be avoided during pregnancy due to potential harm to the baby.
• Kidney or Liver Disease: Caution and dose adjustment are needed in patients with significant kidney or liver impairment.

Natrilam MR 5/1.5 Tablet Side Effects

• Dizziness
• Swelling in the ankles or feet
• Muscle cramps
• Headache
• Fatigue
• Low potassium or sodium levels
• Palpitations
• Flushing

Storage Conditions

• Store at room temperature away from moisture and direct light.
• Keep the tablets in their original blister pack until use.
• Avoid storing in a humid bathroom cabinet.
• Keep out of reach of children.