Nivaquine-P tablet 250mg

About Nivaquine-P tablet 250mg

Nivaquine-P Tablet Uses

• Treatment of malaria caused by susceptible Plasmodium species.
• Prevention of malaria before and during travel to malaria prone areas.
• Use for certain inflammatory joint conditions, under specialist care.

Nivaquine-P Tablet Benefits

• Clearance of malaria parasites from the blood within a few days of starting treatment.
• A long history of use, giving it a well understood safety profile.
• An affordable option for malaria treatment and prevention in Pakistan.

Drug Class

• Antimalarial, 4-aminoquinoline group.

What Experts Say

Malaria remains a seasonal concern in many parts of Pakistan, particularly during and after the monsoon when mosquito breeding increases. Chloroquine phosphate has been used for decades and still works well against sensitive Plasmodium vivax infections. Recognizing the fever pattern early allows treatment to start before the infection becomes more severe.

Doctors confirm the diagnosis with a blood test before starting treatment, since chloroquine resistant Plasmodium falciparum is now common in many regions. Dosing usually follows a short, structured course rather than open ended daily use. Patients who do not improve within the expected timeframe are usually switched to an alternative antimalarial regimen.

Because chloroquine can affect the heart rhythm and the eyes with long term use, doctors avoid repeated or prolonged courses outside malaria prevention. Patients with an irregular heartbeat or existing eye disease need closer monitoring before starting therapy. Baseline eye examinations are sometimes recommended before starting long courses used for non-malarial indications.

Nivaquine-P tablet 250mg formula

• Chloroquine Phosphate 250mg

Available forms

• Tablet

How to use Nivaquine-P tablet 250mg?

• Take Nivaquine-P tablet exactly as prescribed by your doctor.
• Swallow the tablet with food or milk to reduce stomach upset.
• Complete the full course even if symptoms improve early.
• For prevention, start the course before travel as advised by your doctor.

Drug Interactions

• Antacids: Absorption can drop when taken at the same time, so doses should be spaced apart.
• Other Heart Rhythm Medicines: A higher risk of abnormal heart rhythm comes with combined use.
• Methotrexate: A higher risk of side effects may come with combined use.
• Anti-seizure Medicines: The effectiveness of some seizure medicines can drop with chloroquine.

Risks and warnings

• Heart Rhythm: Heart rhythm can be affected, especially with high doses or existing heart disease.
• Eye Health: Vision may be affected with long term or repeated use, so periodic eye checks are advised.
• G6PD Deficiency: Extra caution is needed in patients with this enzyme deficiency.
• Liver Disease: Medical supervision is needed for cautious use.
• Children: Overdose in children can be dangerous, so safe storage of tablets matters.

Nivaquine-P Tablet Side Effects

• Nausea or an upset stomach.
• Headache.
• Dizziness.
• Itching, especially in patients with darker skin.
• Blurred vision with prolonged use.
• Loss of appetite.
• Skin rash.

Storage Conditions

• Store below 30°C in a dry place away from direct sunlight.
• Keep the tablet in its original packaging until use.
• Keep out of reach of children, as overdose can be dangerous.
• Do not use after the expiry date printed on the pack.