About Noclot-EA Tablet 75mg / 75mg
Noclot-EA Tablet combines Clopidogrel and Aspirin, an antiplatelet duo used to prevent cardiovascular blood clots.
Noclot-EA Tablet Uses
- Prevention of heart attack in patients with prior cardiovascular events
- Prevention of ischemic stroke in patients with a history of stroke or TIA
- Management of acute coronary syndrome including unstable angina and NSTEMI
- Prevention of blood clots after coronary stent placement
- Reducing cardiovascular risk in peripheral arterial disease
Noclot-EA Tablet Benefits
- Lowers risk of recurrent heart attack and stroke
- Prevents stent thrombosis after angioplasty procedures
- Reduces cardiovascular death in high-risk patients
- Combines two antiplatelet mechanisms in a single tablet
- Backed by decades of cardiology research and guideline use
What Experts Say
Clopidogrel works as a P2Y12 receptor antagonist that blocks adenosine diphosphate mediated platelet activation, while aspirin inhibits cyclooxygenase-1 to suppress thromboxane A2 production. Combining both agents produces antiplatelet inhibition through two separate pathways, lowering the chance of clot formation inside narrowed or damaged arteries.
Cardiology guidelines support dual antiplatelet therapy after acute coronary syndrome or coronary stent placement because single-agent therapy alone does not sufficiently reduce recurrent ischemic events. Trials show this combination lowers stent thrombosis, myocardial infarction, and ischemic stroke compared with aspirin alone during the months following a cardiac intervention.
This added protection carries a higher bleeding risk than either drug used alone, so treatment duration and patient selection require careful clinical judgment. Physicians weigh ischemic risk against bleeding risk before prescribing extended courses, and abrupt discontinuation is generally avoided since it can trigger rebound platelet activity and acute clot formation.
Drug Class
- Antiplatelet Agent
- P2Y12 Receptor Inhibitor (Clopidogrel)
- Cyclooxygenase Inhibitor (Aspirin)
- Dual Antiplatelet Therapy (DAPT) Combination
Noclot-EA Tablet 75mg / 75mg Uses in Urdu
- دل کے دورے سے بچاؤ کے لیے
- فالج سے بچاؤ کے لیے
- ایکیوٹ کورونری سنڈروم کے علاج میں
- انجیوپلاسٹی یا سٹنٹ کے بعد خون جمنے سے بچاؤ
- پیریفرل آرٹیریل بیماری میں استعمال
Noclot-EA Tablet 75mg / 75mg formula
- Clopidogrel Bisulphate 75mg + Aspirin 75mg
How to use Noclot-EA Tablet 75mg / 75mg?
- Take one tablet by mouth once daily at the same time each day
- Swallow the tablet whole with a glass of water, with or without food
- Do not crush or chew the tablet
- Do not stop this medicine without consulting your doctor, especially after a stent procedure
- Take exactly as prescribed by your cardiologist
Drug Interactions
- Warfarin And Other Anticoagulants: Combined use significantly increases the risk of serious bleeding
- NSAIDs Like Ibuprofen Or Diclofenac: Concurrent use raises the risk of gastrointestinal bleeding and ulceration
- Proton Pump Inhibitors Like Omeprazole: May reduce the antiplatelet effect of clopidogrel by limiting its activation
- SSRIs Like Fluoxetine Or Sertraline: May increase bleeding risk when combined with antiplatelet therapy
- Methotrexate: Aspirin may raise methotrexate blood levels and toxicity
- Corticosteroids: Long-term combined use raises the risk of gastrointestinal ulceration and bleeding
Risks and warnings
- Bleeding Risk: Increases risk of bleeding, including gastrointestinal and intracranial bleeding, especially with prolonged use
- Surgery Precaution: Inform your doctor before any surgery or dental procedure since this medicine may need to be paused temporarily
- Stent Thrombosis Risk: Do not discontinue without medical advice after coronary stent placement, as sudden stoppage can trigger dangerous clot formation
- Peptic Ulcer Disease: Use with caution in patients with a history of stomach ulcers or gastrointestinal bleeding
- Pregnancy And Breastfeeding: Use only if clearly needed and under direct medical supervision
- Renal Or Hepatic Impairment: Use with caution as dose adjustment may be required in kidney or liver disease
Noclot-EA Tablet Side Effects
- Easy bruising or bleeding
- Upset stomach or heartburn
- Nausea and diarrhea
- Headache and dizziness
- Nosebleeds or bleeding gums
- Skin rash or itching
- Blood in urine or stool requiring immediate medical attention
- Unusual tiredness or shortness of breath
Storage Conditions
- Store below 30°C in a cool, dry place away from direct sunlight
- Keep the tablet in its original blister pack until ready to use
- Keep out of reach of children
- Avoid storing in bathrooms or other humid areas