Norplate-S Tablet 75mg/75mg

About Norplate-S Tablet 75mg/75mg

Norplate-S Tablet 75mg/75mg Uses

• Prevention of blood clots after a heart attack
• Prevention of clots after coronary artery stent placement
• Reducing the risk of stroke in people with a history of clotting events
• Used in peripheral artery disease to lower clot related complications

Norplate-S Tablet 75mg/75mg Benefits

• Combines two antiplatelet actions in a single daily tablet
• Reduces the chance of repeat heart attack or stroke
• Supported by strong clinical evidence in cardiovascular disease
• Convenient once daily dosing improves treatment adherence

What Experts Say

Aspirin and clopidogrel work through two different pathways to stop platelets from clumping together and forming dangerous clots inside blood vessels. Aspirin blocks an enzyme called cyclooxygenase, while clopidogrel blocks a receptor called P2Y12 on the platelet surface, giving broader clot protection than either medicine alone.

This dual antiplatelet approach is commonly prescribed after a heart attack, after a stent is placed in a coronary artery, or following certain types of stroke. Doctors usually prescribe this combination for a limited period, since long term dual therapy raises bleeding risk without added benefit for most patients.

Patients are advised to take the tablet at the same time each day and never stop it suddenly without medical advice, since stopping early after a stent can raise the risk of the stent closing off. Any unusual bruising, black stools or prolonged bleeding should be reported to a doctor right away.

Drug Class

• Antiplatelet combination therapy
• COX inhibitor plus P2Y12 receptor blocker
• Cardiovascular protective agent

Norplate-S Tablet 75mg/75mg formula

• Aspirin 75mg
• Clopidogrel Bisulphate 75mg

Available forms

• Tablet

How to use Norplate-S Tablet 75mg/75mg?

• Take one tablet daily at the same time, with or without food
• Swallow the tablet whole with water, do not crush or chew it
• Do not stop taking it suddenly without your cardiologist's advice
• Inform your doctor before any surgery or dental procedure
• Missed doses should be taken as soon as remembered unless it is close to the next dose

Drug Interactions

• NSAIDs: Combining with ibuprofen or other pain relievers raises the risk of stomach bleeding.
• Blood Thinners: Using with warfarin or heparin significantly increases bleeding risk.
• Proton Pump Inhibitors: Some, like omeprazole, may reduce clopidogrel's effectiveness.
• Other Antiplatelets: Combining with additional antiplatelet drugs is generally avoided.

Risks and warnings

• Bleeding Risk: Combination therapy increases the chance of bleeding, including in the stomach and brain.
• Stent Patients: Stopping this medicine early after a stent can raise the risk of sudden clotting.
• Surgery: Usually needs to be paused before planned surgery under medical guidance.
• Stomach Ulcers: Aspirin can worsen or trigger stomach ulcers in susceptible people.
• Kidney Or Liver Disease: Requires caution and dose review in people with reduced organ function.

Norplate-S Tablet 75mg/75mg Side Effects

• Easy bruising
• Nosebleeds
• Stomach upset or heartburn
• Diarrhea
• Prolonged bleeding from small cuts
• Headache
• Skin rash
• Rare but serious internal bleeding

Storage Conditions

• Store below 30 degrees Celsius in a dry place
• Keep the tablets in their original blister pack
• Protect from moisture and direct sunlight
• Keep out of reach of children