Pirexen Tablet 20mg

About Pirexen Tablet 20mg

Pirexen Tablet 20mg Uses

• Osteoarthritis pain and stiffness
• Rheumatoid arthritis
• Ankylosing spondylitis
• Post operative and post traumatic pain and swelling
• Painful periods (dysmenorrhea)

Pirexen Tablet 20mg Benefits

• Faster absorption than plain piroxicam due to the cyclodextrin carrier, giving quicker pain relief
• Long acting formula allows once daily dosing
• Reduces both pain and joint swelling in chronic arthritis
• Useful for short courses of acute pain such as after minor surgery or injury

Drug Class

• Non-Steroidal Anti-Inflammatory Drug (NSAID), oxicam group

What Experts Say

Piroxicam Beta-Cyclodextrin works by non-selectively blocking the COX-1 and COX-2 enzymes that produce prostaglandins, the chemical messengers behind pain, swelling, and fever at sites of tissue injury or joint inflammation. The cyclodextrin carrier improves solubility, giving faster absorption than standard piroxicam tablets.

Piroxicam has a long half-life of nearly 48 hours, so its anti-inflammatory effect builds up over several days of regular use. This makes it effective for chronic joint conditions, but side effects can also persist after stopping, which is why doctors reserve it for short courses rather than continuous long-term use.

Regulatory guidance limits piroxicam to the lowest effective dose for the shortest duration, due to a higher documented risk of stomach ulcers, bleeding, and skin reactions than other oxicam-class drugs. Doctors often pair it with a stomach-protecting medicine for prolonged use and avoid it in the elderly or those with peptic ulcer history.

Pirexen Tablet 20mg formula

• Piroxicam Beta-Cyclodextrin

Available forms

• Tablet

How to use Pirexen Tablet 20mg?

• Take one tablet daily, preferably after a meal to reduce stomach upset
• Swallow the tablet whole with a full glass of water
• Do not exceed the dose prescribed by your doctor
• Use for the shortest duration needed to control symptoms

Drug Interactions

• Blood Thinners: Combining with warfarin or other anticoagulants raises the risk of serious bleeding
• Other NSAIDs Or Aspirin: Taking together increases the risk of stomach ulcers without added pain relief benefit
• Blood Pressure Medicines: Can reduce the effectiveness of ACE inhibitors and diuretics
• Lithium: Piroxicam can raise lithium levels in the blood, increasing the risk of toxicity

Risks and warnings

• Stomach Ulcers: Long term use increases the risk of stomach bleeding and ulcers, especially in older adults
• Heart Risk: NSAIDs including piroxicam can increase the risk of heart attack or stroke with prolonged use
• Skin Reactions: Rare but serious skin reactions have been reported, requiring immediate medical attention if a rash develops
• Pregnancy: Should be avoided in the third trimester of pregnancy due to risk to the unborn baby

Pirexen Tablet 20mg Side Effects

• Stomach pain or indigestion
• Nausea
• Dizziness
• Swelling in the ankles or feet
• Skin rash
• Stomach ulcer or gastrointestinal bleeding
• Raised blood pressure
• Kidney function changes with long term use

Storage Conditions

• Store below 30°C in a dry place away from moisture
• Keep the strip in its original packaging until use
• Keep out of reach of children
• Do not use beyond the expiry date printed on the pack