Plasenzym Tablet

About Plasenzym Tablet

Plasenzym Tablet Uses

• Indigestion and dyspepsia
• Bloating and excessive gas
• Nausea and vomiting linked to slow stomach emptying
• Post meal fullness and delayed gastric emptying

Plasenzym Tablet Benefits

• Speeds up stomach emptying to relieve fullness after meals
• Breaks down proteins and fats for easier digestion
• Reduces trapped gas and bloating
• Combines a prokinetic with digestive enzymes in one tablet

What Experts Say

Physicians in Pakistan combine a prokinetic with digestive enzymes when patients report both delayed stomach emptying and poor digestion of a heavy meal. Metoclopramide speeds gastric emptying by blocking dopamine receptors in the gut, while bromelain and pancreatin supply the protein and starch splitting enzymes that a sluggish digestive system may not produce in sufficient amounts.

Metoclopramide carries a boxed warning for tardive dyskinesia, so physicians generally limit its use to twelve weeks and prefer the lowest effective dose. Patients on long term therapy are usually reviewed for early signs of involuntary movement, and the enzyme components are assessed separately since they do not carry the same restriction.

Heavy, oil rich meals and irregular eating patterns common across Pakistan contribute to a high burden of functional dyspepsia and bloating. A combination tablet appeals to physicians treating patients who need both faster gastric emptying and enzyme support, though an accurate diagnosis first rules out ulcers or other structural causes.

Drug Class

• Gastroprokinetic Agent (Metoclopramide)
• Digestive Enzyme Supplement (Bromelain, Pancreatin)
• Antiflatulent (Simethicone)
• Choleretic (Sodium Dehydrocholate)

Plasenzym Tablet formula

• Metoclopramide Hydrochloride 6mg + Bromelain 35000 P.U. + Pancreatin 210 P.U. + Simethicone 50mg + Sodium Dehydrocholate 50mg

Available forms

• Tablet

How to use Plasenzym Tablet?

• Take one tablet 10 to 15 minutes before each main meal, or as directed by your doctor.
• Swallow the tablet whole with a glass of water.
• Do not exceed the dose or duration prescribed by your physician.
• Take with food if stomach upset occurs.

Drug Interactions

• Anticholinergics And Narcotics: These can reduce the prokinetic effect of metoclopramide on the stomach.
• Antipsychotics: Combining with other dopamine blocking drugs raises the risk of movement disorders.
• Blood Thinners: Bromelain may add to the effect of warfarin and other anticoagulants, increasing bleeding risk.
• MAO Inhibitors: Concurrent use with metoclopramide can raise blood pressure and is generally avoided.
• Alcohol And Sedatives: These can worsen the drowsiness caused by metoclopramide.

Risks and warnings

• Tardive Dyskinesia: Long term or high dose use of metoclopramide can cause involuntary, sometimes irreversible muscle movements.
• Drowsiness: This tablet can cause sedation, so avoid driving or operating machinery until you know how it affects you.
• Bleeding Risk: Bromelain may increase bleeding tendency in patients on blood thinners or with bleeding disorders.
• Bowel Obstruction: Do not use if you have gastrointestinal bleeding, obstruction, or perforation.
• Pregnancy: Avoid use during the first trimester unless your doctor advises otherwise.

Plasenzym Tablet Side Effects

• Drowsiness or fatigue
• Restlessness or insomnia
• Diarrhea or loose stools
• Headache or dizziness
• Mild stomach upset
• Involuntary muscle movements with prolonged use
• Allergic skin reactions such as itching or rash

Storage Conditions

• Store the tablets at room temperature below 30 degrees Celsius.
• Keep the strip in its original packaging away from direct light.
• Protect from moisture by keeping in a dry place.
• Keep out of reach of children.
• Discard any tablets past the expiry date printed on the pack.