Plasil With Enzyme Tablet

About Plasil With Enzyme Tablet

Plasil With Enzyme Tablet Uses

• Nausea and vomiting linked to stomach and digestive problems
• Functional dyspepsia and indigestion
• Post-meal fullness and heaviness
• Bloating, gas, and flatulence
• Heartburn and gastric backflow symptoms
• Digestive discomfort in gastritis

Plasil With Enzyme Tablet Benefits

• Controls nausea and vomiting through its metoclopramide content
• Speeds up stomach emptying, which eases post-meal heaviness
• Supports digestion of fats, proteins, and starch with pancreatin and bromelain
• Reduces trapped gas and bloating through simethicone
• Promotes bile flow, which helps the body process fatty meals
• Combines antiemetic and digestive support in a single tablet

What Experts Say

Metoclopramide is a dopamine receptor antagonist that works as a prokinetic and antiemetic agent. Clinical evidence shows it speeds up gastric emptying and blocks signals in the chemoreceptor trigger zone, which reduces nausea and vomiting arising from stomach and digestive causes.

The enzyme blend adds digestive support to this antiemetic action. Pancreatin supplies amylase, lipase, and protease for the breakdown of starch, fat, and protein. Bromelain assists protein digestion, simethicone disperses trapped gas bubbles, and sodium dehydrocholate promotes bile flow, which supports fat absorption.

Functional dyspepsia and post-meal bloating are frequent complaints in Pakistani clinics, and they often follow heavy, spicy, or fried meals. Doctors in Pakistan usually reserve this combination for short courses, since prolonged metoclopramide use raises the risk of movement-related side effects. Medical review is advised if symptoms persist beyond a few days of treatment.

Drug Class

• Prokinetic Antiemetic + Digestive Enzyme Combination

Plasil With Enzyme Tablet formula

• Metoclopramide 6mg + Pancreatin 210 FIP Units + Bromelain 35,000 Units + Dimethylpolysiloxane (Simethicone) 50mg + Sodium Dehydrocholate 20mg

Available forms

• Tablet

How to use Plasil With Enzyme Tablet?

• Take Plasil With Enzyme Tablet exactly as prescribed by your doctor.
• The usual dose is one tablet three times a day, taken with or just before meals.
• Swallow the tablet whole with a glass of water, and do not crush or chew it.
• Do not take more tablets in 24 hours than your doctor has advised.
• Use it for the shortest duration advised, since long-term metoclopramide use is not recommended.
• Contact your doctor if nausea, vomiting, or bloating does not settle within a few days.

Drug Interactions

• Levodopa: Metoclopramide and levodopa oppose each other's effects, so the combination is avoided.
• Anticholinergic medicines: Drugs like hyoscine reduce the gut-stimulating effect of this tablet.
• Sedatives & alcohol: Combined use increases drowsiness and slows reaction time.
• Digoxin: Metoclopramide can lower digoxin absorption and reduce its effect.
• Antipsychotics: Taking two dopamine-blocking medicines raises the risk of movement side effects.
• SSRI antidepressants: Combined use raises the risk of serotonin syndrome and movement reactions.

Risks and warnings

• Movement disorders: Long-term or high-dose use can cause tremors, muscle stiffness, or uncontrolled facial movements.
• Stomach or bowel blockage: Avoid this medicine if you have suspected gastrointestinal obstruction, bleeding, or perforation.
• Drowsiness: The tablet can cause sleepiness, so avoid driving or operating machinery until you know how it affects you.
• Seizure disorders: Metoclopramide can worsen seizure control in people with epilepsy.
• Parkinson's disease: Avoid use in this condition because dopamine blockade may worsen symptoms.
• Pregnancy & breastfeeding: Use only if your doctor confirms the benefit outweighs the risk.
• Enzyme allergy: People allergic to pancreatin, bromelain, or pineapple-derived products should inform their doctor first.

Plasil With Enzyme Tablet Side Effects

• Drowsiness or sleepiness
• Tiredness and weakness
• Restlessness or agitation
• Headache
• Dizziness
• Diarrhea or loose stools
• Dry mouth
• Muscle spasms of the face, neck, or tongue
• Breast tenderness or milk secretion from raised prolactin
• Menstrual irregularities
• Low mood with prolonged use
• Skin rash in sensitive individuals

Storage Conditions

• Store below 30°C in a cool, dry place.
• Protect the tablets from direct sunlight, heat, and moisture.
• Keep the tablets in the original blister pack until use.
• Keep the medicine out of the reach and sight of children.
• Do not use tablets after the expiry date printed on the pack.