Profylline Syrup 100mg

About Profylline Syrup 100mg

Profylline Syrup Uses

• Relieves wheezing and breathlessness in bronchial asthma
• Eases airway narrowing in chronic obstructive pulmonary disease (COPD)
• Used as add on therapy for chronic bronchitis with reversible airway obstruction
• Helps control recurrent breathing difficulty in children with asthma when prescribed by a pediatrician

Drug Class

• Xanthine derivative bronchodilator

What Experts Say

Doxofylline belongs to the xanthine family of bronchodilators, the same group as theophylline. Physicians favor it because it relaxes the smooth muscles lining the airways without strongly binding to adenosine receptors, the mechanism responsible for many of theophylline's cardiac and gastrointestinal side effects.

Pulmonologists in Pakistan often prescribe doxofylline syrup for patients who need an oral bronchodilator but cannot tolerate the palpitations, insomnia, or stomach upset that theophylline sometimes causes. Its favorable safety profile makes it suitable for longer courses of treatment in chronic respiratory disease.

Because Pakistan carries a significant burden of asthma and chronic bronchitis linked to air pollution and biomass fuel exposure, doctors emphasize consistent dosing and regular follow-up when prescribing xanthine bronchodilators. Blood pressure and heart rate are monitored periodically, especially in patients taking other stimulant medicines together.

Profylline Syrup 100mg formula

• Doxofylline 100mg

Available forms

• Syrup

How to use Profylline Syrup 100mg?

• Take Profylline Syrup exactly as prescribed by your doctor, usually two to three times a day
• Measure the dose with the marked measuring cup provided, not a regular kitchen spoon
• Take it after meals to reduce stomach irritation
• Shake the bottle well before each use
• Do not stop the syrup suddenly without consulting your doctor, even if symptoms improve

Drug Interactions

• Macrolide Antibiotics: Erythromycin and clarithromycin can raise doxofylline blood levels
• Allopurinol: May increase the risk of doxofylline side effects
• Other Xanthine Drugs: Combining with theophylline or aminophylline raises toxicity risk
• Beta Blockers: Propranolol can slow doxofylline clearance from the body
• Caffeine: Heavy caffeine intake can add to jitteriness and palpitations

Risks and warnings

• Heart Conditions: Use with caution in patients with arrhythmia or uncontrolled hypertension
• Liver Disease: Doxofylline is processed by the liver, so dosing may need adjustment in liver impairment
• Peptic Ulcer: May worsen acid reflux or ulcer symptoms in sensitive patients
• Pregnancy and Breastfeeding: Use only if clearly needed and advised by a doctor
• Seizure Disorders: Xanthine bronchodilators can lower the seizure threshold in susceptible patients
• Children: Dose must be calculated by body weight and supervised by a pediatrician

Profylline Syrup Side Effects

• Nausea or stomach upset
• Headache
• Palpitations or a fast heartbeat
• Restlessness or difficulty sleeping
• Dizziness
• Skin rash in rare cases

Storage Conditions

Store below 25 degrees Celsius in a cool, dry place away from direct sunlight. Keep the bottle tightly closed and out of reach of children. Discard any unused syrup after the expiry date on the pack.