Renavel Capsule 400mg

About Renavel Capsule 400mg

Renavel Capsule 400mg Uses

• High phosphate levels in chronic kidney disease
• Phosphate control in patients on hemodialysis
• Phosphate control in patients on peritoneal dialysis

Renavel Capsule 400mg Benefits

• Binds dietary phosphate in the gut before it enters the blood
• Does not add calcium load to the body
• Helps protect bones and blood vessels from calcium phosphate buildup
• Supports long term kidney disease management

What Experts Say

Sevelamer hydrochloride works inside the digestive tract by binding to phosphate from food before it can be absorbed into the bloodstream. This action lowers serum phosphate levels without raising blood calcium, which sets it apart from older calcium based binders that carry a risk of vascular calcification over long term use.

Patients with chronic kidney disease often lose the ability to clear excess phosphate through urine, and over time this imbalance can lead to weakened bones and calcium deposits in blood vessels and heart tissue. Sevelamer helps slow this process when taken consistently with every meal that contains phosphate rich food.

Because the medication works locally in the gut rather than being absorbed into the body, it needs to be taken with food to be effective and is generally not associated with the systemic side effects seen with some other renal medications. Regular blood tests are still recommended to track phosphate, calcium and overall kidney function during treatment.

Drug Class

• Phosphate binder
• Non calcium based renal agent

Renavel Capsule 400mg formula

• Sevelamer Hydrochloride 400mg

Available forms

• Capsule

How to use Renavel Capsule 400mg?

• Take with meals or immediately after eating
• Usual starting dose is one to two capsules three times daily with food
• Swallow the capsule whole with water
• Do not open or crush the capsule
• Dose is adjusted based on regular phosphate blood test results

Drug Interactions

• Ciprofloxacin: Absorption of this antibiotic may be reduced if taken at the same time
• Thyroid Medication: Levothyroxine absorption may be lowered, so dosing times should be separated
• Immunosuppressants: Cyclosporine and similar drugs may be affected and need spaced dosing
• Other Oral Medicines: General practice is to take other important oral drugs at least one hour before or three hours after this medicine

Risks and warnings

• Bowel Obstruction: Avoid use if you have a history of bowel obstruction or major gastrointestinal surgery
• Swallowing Difficulty: Use caution in patients with swallowing problems since the capsule must be swallowed whole
• Low Phosphate: Regular monitoring is needed to avoid phosphate levels dropping too low
• Vitamin Deficiency: Long term use may lower fat soluble vitamin levels such as vitamin D and vitamin K
• Pregnancy: Use only if clearly needed and under medical supervision

Renavel Capsule 400mg Side Effects

• Nausea
• Vomiting
• Diarrhea
• Constipation
• Abdominal pain
• Bloating
• Headache
• Low blood pressure

Storage Conditions

• Store at room temperature below 30 degrees Celsius
• Keep in a dry place away from moisture
• Keep the strip inside its original carton until use
• Keep out of reach of children